Noninvasive Cardiac Imaging in Pulmonary Hypertension

Sallach, Susan M.; Peshock, Ronald M; Reimold, Sharon C.

doi:10.1097/01.crd.0000253644.43837.d7

Cited by 15 publications

(12 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Continuing improvements in MRI spatial and temporal resolution, as well as in algorithms for post-acquisition data analysis, make it likely that cardiovascular MRI (alone and in combination with echocardiography) will largely supplant invasive techniques in the future. A comparison of the utility of cardiovascular MRI versus echocardiography for measuring different parameters important in PAH is shown in Table 2 (56). Table 3 shows a comparison of the utility of different imaging modalities and RHC for providing information about various cardiac parameters.…”

Section: Cardiovascular Mri In Pah: Strengths and Weaknessesmentioning

confidence: 99%

Role of Cardiac Magnetic Resonance Imaging in the Management of Patients With Pulmonary Arterial Hypertension

Benza

Biederman

Murali

et al. 2008

Journal of the American College of Cardiology

170

107

View full text Add to dashboard Cite

Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by abnormally elevated blood pressure of the pulmonary circulation that results, over time, from extensive vascular remodeling and increased pulmonary vascular resistance. Recent advances in magnetic resonance imaging (MRI) technology have led to the development of techniques for noninvasive assessment of cardiovascular structure and function, including hemodynamic parameters in the pulmonary circulation, which are superior in their identification of right ventricular morphologic changes. These advantages make cardiac MRI an attractive modality for following up and providing prognoses in patients with PAH. In this review, we summarize recent developments in the use of MRI for the diagnosis, assessment, and ongoing monitoring of patients with PAH. Over the coming decade, it can be anticipated that continued improvements in MRI image acquisition, spatial and temporal resolution, and analytical techniques will result in improved understanding of PAH pathophysiology, diagnosis, and prognostic variables, and will supplement, and may even replace, some of the invasive procedures currently applied routinely to the evaluation of PAH.

show abstract

Section: Cardiovascular Mri In Pah: Strengths and Weaknessesmentioning

confidence: 99%

Role of Cardiac Magnetic Resonance Imaging in the Management of Patients With Pulmonary Arterial Hypertension

Benza

Biederman

Murali

et al. 2008

Journal of the American College of Cardiology

170

107

View full text Add to dashboard Cite

show abstract

“…Given the improved survival rates in adults with PAH compared with historical cohorts, additional outcome measures (such as quality of life) [35][36][37] and noninvasive end-points (such as biochemical markers, e.g. brain natriuretic peptide (BNP) [38]) and echocardiographic or magnetic resonance imaging have attracted increasing interest [39][40][41].…”

Section: Outcome Measures In Paediatric Phmentioning

confidence: 99%

Paediatric pulmonary hypertension: monitoring progress and identifying unmet needs

Beghetti¹

2009

Eur Respir Rev

View full text Add to dashboard Cite

Recent advances in the field of pulmonary hypertension (PH) have provided clinicians with a range of treatment options, but effective disease management in children presents a unique challenge. The present article will discuss the steps being taken to address unmet needs in paediatric PH.Understanding the epidemiology of paediatric PH is essential to guide management decisions, but such epidemiological data are scarce. The first international paediatric PH registry, Tracking Outcomes in Paediatric Pulmonary Hypertension (TOPP), promises to become a vital resource.Studies of PH therapies are rare in children, and treatment of paediatric PH is generally guided by the adult treatment algorithm, with some adaptations. However, invasive management options, such as continuous prostacyclin infusion, even if effective, are challenging in children, and further research is required to develop appropriate treatment strategies, formulations and doses for paediatric PH. Measures of treatment success must also be defined, and the applicability of endpoints from adult clinical studies remains an open question.In summary, further epidemiological and treatment data are needed for paediatric pulmonary hypertension. The international TOPP registry will provide a valuable insight, but this must be complemented by research and development of adapted paediatric therapies. Dedicated childhood pulmonary hypertension services would optimise the diagnosis and management of this life-threatening disease.

show abstract

“…The complex user interface for the instrument requires considerable operator training. The lack of standardised protocols and viewing formats put a burden on each imaging centre to develop their own, but this is being corrected (66). Finally, the focus towards using cardiovascular CMR for research means that billing codes for procedures are suboptimal and have not kept up with technological advances.…”

Section: Cardiovascular Cmr In Pah: Strengths and Weaknessesmentioning

confidence: 99%

Cardiovascular magnetic resonance imaging as applied to patients with pulmonary arterial hypertension

Biederman

2009

International Journal of Clinical Practice

View full text Add to dashboard Cite

Summary Numerous imaging techniques are currently used to evaluate pulmonary arterial hypertension (PAH), including echocardiography, x‐ray, electrocardiogram (ECG), computed tomography and magnetic resonance imaging (MRI). All such modalities have inherent advantages and disadvantages governed by physical principles that result in their clinical utility. In that PAH is a progressive disorder characterised by abnormally elevated blood pressure of the pulmonary circulation that leads to extensive vascular remodelling and increased pulmonary vascular resistance, a technique that can encapsulate those specific features that depict the multiple facets of this disease has obvious advantages. Recent advances in cardiovascular MRI (CMR) technology have led to the development of dedicated techniques for non‐invasive assessment of cardiovascular structure and function, including haemodynamical parameters in the pulmonary circulation, which are superior in their identification of pulmonary arterial right ventricular morphological changes. These advantages make CMR a very attractive modality for diagnosing, following and providing prognoses for PAH patients. In this review, we highlight the developments in the use of CMR for the diagnosis, assessment and monitoring of patients with PAH. These remarkable improvements in image acquisition, physiological imaging and contrast techniques place CMR in a prime position for defining this disease. In the coming decade, it is anticipated that continued improvements in CMR image acquisition, spatial and temporal resolution and analytical techniques will result in improved understanding of PAH pathophysiology, diagnosis and prognostic variables, as well as the replacement of the most, if not all, invasive procedures currently applied routinely to the evaluation of PAH.

show abstract

Noninvasive Cardiac Imaging in Pulmonary Hypertension

Cited by 15 publications

References 16 publications

Role of Cardiac Magnetic Resonance Imaging in the Management of Patients With Pulmonary Arterial Hypertension

Role of Cardiac Magnetic Resonance Imaging in the Management of Patients With Pulmonary Arterial Hypertension

Paediatric pulmonary hypertension: monitoring progress and identifying unmet needs

Cardiovascular magnetic resonance imaging as applied to patients with pulmonary arterial hypertension

Contact Info

Product

Resources

About