Noninvasive determination of atrial fibrillation cycle length by atrial colour tissue <scp>D</scp>oppler imaging in horses

Decloedt, Annelies; Clercq, Dominique De; Vekens, Nicky Van Der; Verheyen, Tinne; Loon, Gunther van

doi:10.1111/evj.12108

Cited by 17 publications

(34 citation statements)

References 35 publications

(41 reference statements)

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“…The AFCL measured in the left atrial free wall from the right parasternal 4‐chamber view was shorter compared to the other views, as has been described previously . The AFCL from this view did not show a significant increase after sotalol administration.…”

Section: Discussionsupporting

confidence: 78%

“…The atrial fibrillatory rate was assessed from tissue Doppler velocity curves of the atrial myocardial walls, as described previously . In brief, tissue Doppler images were acquired from the left atrial free wall in a right parasternal 4‐chamber view, from the right atrial dorsal wall at the level of the tuberculum intervenosum in a right parasternal view and from the left atrial free wall in a left parasternal long axis view.…”

Section: Methodsmentioning

confidence: 99%

“…Tissue Doppler velocity curves were acquired off‐line by positioning a 5 × 5 mm sample volume in the atrial myocardial wall (Echopac software version 11.2, GE Healthcare, Diegem, Belgium). The atrial fibrillation cycle length (AFCL) was measured from consecutive loops with at least moderate quality, until a minimum of 30 AFCL were measured from each view (Figure ) . These 30 measurements then were averaged to obtain AFCL from each view.…”

Section: Methodsmentioning

confidence: 99%

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Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation

Decloedt

Broux

Clercq

et al. 2018

Veterinary Internal Medicne

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BackgroundBased on its pharmacokinetic profile and electrophysiological effects in healthy horses, sotalol potentially could be used as a long‐term PO antiarrhythmic drug in horses.ObjectivesTo evaluate the effect of sotalol on heart rate (HR), QT interval, atrial fibrillatory rate, and success of cardioversion in horses with naturally occurring chronic atrial fibrillation (AF).AnimalsTwenty‐eight horses referred for transvenous electrical cardioversion of AF were treated with 2 mg/kg sotalol PO q12h for 3 days before cardioversion, and 13 horses underwent the same protocol without sotalol administration.MethodsRetrospective study. Before and after sotalol or no treatment, the HR was measured at rest and during an exercise test. The QT interval and atrial fibrillation cycle length (AFCL) were measured at rest using tissue Doppler velocity imaging.ResultsIn the control group, no significant differences were found between the 2 examinations. In the sotalol group, the HR at rest and during exercise was significantly lower after sotalol treatment, whereas the QT interval and AFCL measured by tissue Doppler increased significantly. Cardioversion to sinus rhythm was achieved in 25/28 horses in the sotalol group and all horses in the control group, but the median number of shocks and energy at cardioversion were significantly lower in the sotalol group.Conclusions and Clinical ImportanceIn horses with AF, sotalol administration results in class III antiarrhythmic effects and β‐blocking activity, with moderate HR reduction during exercise.

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Section: Discussionsupporting

confidence: 78%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation

Decloedt

Broux

Clercq

et al. 2018

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…The AFCL EGM measurements were performed in the right atrium, while most AFCL TDI measurements were performed in the left atrium. A left‐to‐right gradient of atrial fibrillatory rate has been described previously in horses, with significantly shorter AFCL in the left atrial free wall compared with the right atrial wall . These spatial differences might explain the bias between AFCL EGM and AFCL TDI measurements.…”

Section: Discussionmentioning

confidence: 53%

“…The main limitation of this study is the absence of data on the repeatability of AFCL measurements, although the variability of TDI measurements of atrial contractile function has previously been demonstrated to be low to moderate, and AFCL measurements by TDI have been validated against AFCL measurements by intracardiac EGM . It cannot be excluded that the effect of sedation seen in this study is in fact a time‐related placebo effect, because measurements with sedation were always performed after those without sedation.…”

Section: Discussionmentioning

confidence: 88%