Noninvasive diagnosis of cardiac rejection through echocardiographic tissue characterization

Lieback, E.; Meyer, R.; Nawrocki, M.; Bellach, Joachim; Hetzer, Roland

doi:10.1016/0003-4975(94)91348-x

Cited by 17 publications

(4 citation statements)

References 13 publications

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“…Echokardiographie Valantine et al [16] 15% ↓ isovolumetrische Relaxationszeit oder 82 79 Druckhalbwertszeit Park et al [17] 20% ↑ Te 80 94 Lieback et al [18] Strukturanalyse 89 84 Moidl et al [19] Maximale Füllungsrate ≥ 4,0 EDV/s 100 70 Dandel et al [20] "Pulsed-wave Doppler tissue"-Verfahren; frühe diastolische 84 95 mittlere Wandakzeleration > 10%…”

Section: Ekgunclassified

Diagnostische Wertigkeit von EKG-Veränderungen bei akuten kardialen Abstoßungsreaktionen nach orthotoper Herztransplantation

Tenderich

Jahanyar²,

Zittermann³

et al. 2006

Med Klin

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Section: Ekgunclassified

Diagnostische Wertigkeit von EKG-Veränderungen bei akuten kardialen Abstoßungsreaktionen nach orthotoper Herztransplantation

Tenderich

Jahanyar²,

Zittermann³

et al. 2006

Med Klin

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“…This method has been used successfully to quantify altered myocardial ultrasonic properties in amyloidosis, 10 myocardial damage caused by contusion, 9 and cardiac rejection. 11 Using this method, we were able to detect increased entropy values in contrastenhanced infarcted segments. Ischemia and subsequent reperfusion injury, including edema, hemorrhage, and loss of vascular integrity, cause derangement of microvascular structure and distribution, which should lead to spatial heterogeneity of microbubble distribution, resulting in an altered texture of the contrast-enhanced image.…”

Section: Altered Texture In Infarcted But Opacified Myocardiummentioning

confidence: 77%

Assessment of Myocardial Postreperfusion Viability by Intravenous Myocardial Contrast Echocardiography

et al. 2001

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Background-Although defects on intracoronary myocardial contrast echocardiography (MCE) indicate loss of viability after reperfusion, opacified segments may also exhibit persistent dyssynergy. Therefore, we related the intensity and texture of opacification produced by an intravenous contrast agent to histological findings to determine the characteristics of necrotic tissue by postreperfusion MCE. Methods and Results-MCE was performed by intravenous injection of 0.15 mL/kg QW7437 in 14 dogs who underwent 3-hour coronary occlusion followed by 3-hour reperfusion. At baseline and 3 hours after reperfusion, midventricular short-axis images were digitized and segmented. Infarction fraction (IF) for each segment was determined by triphenyltetrazolium chloride stain. Of 224 segments, 140 showed no or small infarction and served as a control group. Of 84 segments with significant infarction (IFϾ30%), 52 exhibited a defect on MCE, and 32 exhibited no defect. Echo texture was quantified by computing entropy based on the co-occurrence matrix analysis of gray-level pairs within each segment. Three hours after reperfusion, average and maximal entropies in the infarct segments without opacification defects were significantly higher than control levels. Histologically, the degree of intracapillary erythrocyte stasis was less in this group than in the infarcted segments with MCE defects with similar magnitude of tissue injuries. Conclusions-Opacification defects by MCE may be present or absent in myocardium with histologically confirmed infarction. The texture of MCE from opacified but infarcted myocardium differed significantly from control segments and may assist in determination of segmental viability after reperfusion.

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“…In der Literatur sind die verschiedensten echokardiographischen Kriterien zu finden, anhand derer Abstoßungsreaktionen bestimmt werden können (10, 27,29,40 Die Nichtinvasivität der Methode ist ein Vorteil, der zusammen mit den besseren Ergebnissen und der dichten Überwachung schwer statistisch zu quantifizieren ist. Bei herztransplantierten Kindern oder Jugendlichen ist eine Biopsie jedoch häufig nicht durchzuführen oder mit einem hohen Risiko verbunden (19).…”

Section: Biopsieunclassified

“…In der Literatur sind die verschiedensten echokardiographischen Kriterien zu finden, anhand derer Abstoßungsreaktionen bestimmt werden können (10, 27,29,40)…”

Section: Biopsieunclassified

Nicht-invasive Überwachung von Abstoßungsreaktionen nach Herztransplantation

Müller¹,

Dandel²,

Hummel³

et al. 2001

Dtsch med Wochenschr

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Noninvasive diagnosis of cardiac rejection through echocardiographic tissue characterization

Cited by 17 publications

References 13 publications

Diagnostische Wertigkeit von EKG-Veränderungen bei akuten kardialen Abstoßungsreaktionen nach orthotoper Herztransplantation

Diagnostische Wertigkeit von EKG-Veränderungen bei akuten kardialen Abstoßungsreaktionen nach orthotoper Herztransplantation

Assessment of Myocardial Postreperfusion Viability by Intravenous Myocardial Contrast Echocardiography

Nicht-invasive Überwachung von Abstoßungsreaktionen nach Herztransplantation

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