Noninvasive fecal metabolic profiling for the evaluation of characteristics of thermostable lactic acid bacteria, Weizmannia coagulans SANK70258, for broiler chickens

Ito, Kayo; Miyamoto, Hirokuni; Matsuura, Makiko; Ishii, Chitose; Tsuboi, Arisa; Tsuji, Naoko; Nakaguma, Teruno; Nakanishi, Yumiko; Kato, Tamotsu; Suda, Wataru; Honda, Fuyuko; Ito, Toshiyuki; Moriya, Shigeharu; Shima, Hideaki; Michibata, Ryounosuke; Yamada, Ryouichi; Takahashi, Yosuke; Koga, Hirohisa; Kodama, Hiroaki; Watanabe, Yuko; Kikuchi, Jun; Ohno, Hiroshi

doi:10.1016/j.jbiosc.2022.05.006

Cited by 9 publications

(9 citation statements)

References 91 publications

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“…First, for broiler health care, we present a case study of a traditional intestinal regulator [37] . The effect of a heat-stable lactic acid bacterium, Weizmannia coagulans , on the intestinal metabolism of broilers was evaluated by correlation network analysis, and particularly the effect of the said lactic acid bacterium on the administration of the bacterium was shown to alter the diversity of metabolites.…”

Section: Applications To Various Ecosystemsmentioning

confidence: 99%

“…The control of the balance between nitrogen and phosphorus is closely related to biodiversity. Generally, it is difficult to evaluate the viewpoint of biological diversity, and methods based on DNA classification, mainly targeting microorganisms [34] , [35] , methods focusing on metabolites [36] , [37] , or combinations [20] , [38] are performed. Land research has advanced in assessing diversity on land and sea, and it has been pointed out that at least the diversity of soil symbionts is extremely important in the animal-plant-human relationship [39] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An evaluation of homeostatic plasticity for ecosystems using an analytical data science approach

Miyamoto¹,

Kikuchi²

2023

Computational and Structural Biotechnology Journal

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Section: Applications To Various Ecosystemsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

An evaluation of homeostatic plasticity for ecosystems using an analytical data science approach

Miyamoto¹,

Kikuchi²

2023

Computational and Structural Biotechnology Journal

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“…In addition to the direct effects of probiotics on chicken physiology, they produce various metabolites, including SCFAs ( Ito et al ., 2022 ; Ricke, 2003 ), organic acids ( Herzallah, 2013 ), bacitracin ( Smialek et al , 2018 ), and enzymes ( Kalathinathan and Kodiveri Muthukaliannan, 2021 ; Shehata et al , 2022 ), which can regulate host metabolism. Enzymes are among the main intestinal metabolites that promote growth and improve the application of probiotics ( Zhang et al.…”

Section: Beneficial Properties and Applications Of Probiotics In Chic...mentioning

confidence: 99%

“…The primary metabolic products of Bifidobacteria are acetate and lactate, which inhibit the invasion of pathogenic microbes ( Plaza-Diaz et al , 2019 ). After broilers were continuously supplanted with Weizmannia coagulans SANK70258, the fecal metabolites were found to be altered, along with increased propionate and butyrate contents, which may be associated with growth-promoting functions ( Ito et al , 2022 ). Dietary supplementation with Lactobacillus and Rhodobacter capsulatus could increase polyunsaturated fatty acid concentrations and reduce cholesterol levels in chickens ( Selma et al , 2007 ; Kalavathy et al , 2008 ; Ramasamy et al.…”

Section: Beneficial Properties and Applications Of Probiotics In Chic...mentioning

confidence: 99%

Regulatory Effects of the Probiotic <i>Clostridium butyricum</i> on Gut Microbes, Intestinal Health, and Growth Performance of Chickens

et al. 2023

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Clostridium butyricum is an important probiotic for chickens and exerts various biological activities, including altering the composition of the intestinal microbiota, competing with other microorganisms for nutrients, improving the integrity of the intestinal mucosal system, changing the intestinal barrier, and improving overall host health. Intestinal microbes also play vital roles in maintaining the intestinal barrier, regulating intestinal health, and promoting chicken growth. During chicken production, chickens are vulnerable to various stressors that have detrimental effects on the intestinal barrier with significant economic consequences. C. butyricum is a known probiotic that promotes intestinal health and produces the short-chain fatty acid butyric acid, which is beneficial for the growth performance of chickens. This review elucidates the development and utilization of C. butyricum to improve intestinal barrier function and growth performance in chickens through its probiotic properties and interactions with intestinal microbes.

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“…Bacillus coagulans SANK70258 (B. coagulans SANK70258), also termed Weizmannia coagulans SANK70258, is a lactic acid bacterium used as probiotics for livestock animals and humans. Oral administration of B. coagulans SANK70258 effectively promotes the growth of broiler chickens with conferring the protection ability against Coccidia infection [2,3] and modulates the composition of SCFAs in the intestine [4]. A study using a model culture system of human colonic microbiota revealed that B. coagulans SANK70258 increased the concentration of butyrate and number of Lachnospiraceae bacteria in the intestine and reduced colonic Enterobacteriaceae species [5].…”

Section: Introductionmentioning

confidence: 99%

Immunostimulatory effects ofBacillus coagulansSANK70258

Ikeda

Ito

Yamashita

et al. 2023

Preprint

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Specific intestinal bacteria modulate immunoresponses through various pathways, and several probiotic bacteria have been identified as immunostimulants by screening. In the present study, we evaluated the immunomodulating effects ofBacillus coagulansSANK70258 (B. coagulansSANK70258), a spore-forming and lactic acid-producing bacterium usable as food supplement for human and animals. We found that treatment of mouse splenocytes with γ-ray irradiatedB. coagulansSANK70258 induced high amount of IFN-γ in comparison with 7 kinds of typical lactic acid bacteria. Further analyses using splenocytes revealed that NK cell is a major source of IFN-γ, andB. coagulansSANK70258-induced IFN-γ production was inhibited by neutralization of IL-12 or IL-23, depletion of CD11c+cells, and inhibition of NFκB.B. coagulansSANK70258 also induced release of IFN-γ from activated CD8+T cells, and increased expression of chemokine receptors in CD8+T cells.B. coagulansSANK70258-treatment induced production of cytokines from bone marrow-derived dendritic cells, which is reduced by knockdown ofTlr2andNod2.B. coagulansSANK70258-treatment also induced IgA production from Peyer′s patch cells with high level among tested lactic bacteria. The oral intake of γ-ray irradiatedB. coagulansSANK70258 significantly increased intestinal IgA levels and IgA-expressing B cells in the Peyer′s patch of mice. Taken together, we conclude thatB. coagulansSANK70258 possesses high activity as immunostimulant inducing production of IFN-γ and IgA.

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Noninvasive fecal metabolic profiling for the evaluation of characteristics of thermostable lactic acid bacteria, Weizmannia coagulans SANK70258, for broiler chickens

Cited by 9 publications

References 91 publications

An evaluation of homeostatic plasticity for ecosystems using an analytical data science approach

An evaluation of homeostatic plasticity for ecosystems using an analytical data science approach

Regulatory Effects of the Probiotic <i>Clostridium butyricum</i> on Gut Microbes, Intestinal Health, and Growth Performance of Chickens

Immunostimulatory effects ofBacillus coagulansSANK70258

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