Noninvasive Mechanical Ventilation

Esquinas, António M.

doi:10.1007/978-3-319-21653-9

Cited by 6 publications

(1 citation statement)

References 19 publications

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“…A delayed start of NIV increases mortality 9 . Improper selection of patients and continuing treatment when NIV is not sufficient leads to unnecessary harm to the patients and delayed intubation and invasive mechanical ventilation, which is associated with increased mortality 10 .…”

Section: Introductionmentioning

confidence: 99%

Limitations of care and comorbidities are associated with increased mortality in patients treated with non-invasive ventilation: A retrospective observational study in a single-center ICU.

2021

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Background: Non-invasive ventilation (NIV) is a common treatment for acute respiratory failure in intensive care units (ICU). While there is increasing data on outcomes after NIV treatment, there are large variations in staffing and monitoring where NIV is provided, making results hard to generalize. The aim of this study was to characterize patients treated with NIV, describe outcomes, and identify factors associated with outcome in an ICU at a Swedish county hospital. Methods: A single-centre retrospective observational study during 2018 of patients treated with NIV in a six-bed ICU at a Swedish county hospital. Patient characteristics, including comorbidities, details of ICU stay, simplified acute physiology score (SAPS-3), details of NIV treatment and 30-day mortality were collected, and the Charlson co-morbidity index (CCI) was calculated. Primary outcomes were 30-day mortality and associated factors. Results: 92 patients with mean age (71,3, SD 12,1) were treated with NIV during the study period. 42 (46%) were women. Median CCI was 3 (25th-75th percentiles 1.4)) and median SAPS-3 score was 66 (25th-75th percentiles 58). The 30-day mortality was 37% and in the univariate analysis, SAPS-3 score >66, Charlson comorbidity index, CCI>=3, pCO2 <5.5 and limitation of care were factors associated with increased 30-day mortality. pH <7.35 and pO2<8 at admission showed no associations with 30-day mortality. Conclusions: We found that patients treated with NIV in ICU were a diverse population where comorbidities and presence of limitations of care might be considered as better predictors of 30-day mortality, rather than physiological parameters.

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Section: Introductionmentioning

confidence: 99%

Limitations of care and comorbidities are associated with increased mortality in patients treated with non-invasive ventilation: A retrospective observational study in a single-center ICU.

2021

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Monitoring Practical Options: Pharmacology and Noninvasive Mechanical Ventilation

Sabuncu

2023

Noninvasive Ventilation. The Essentials

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Comparison of high‐flow oxygenation with noninvasive ventilation in COPD exacerbation: A crossover clinical trial

Rezaei

Fakharian

Ghorbani

et al. 2020

Clinical Respiratory J

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Objectives To compare the therapeutic effects of high‐flow‐oxygen‐Therapy (HFT) and noninvasive‐ventilation (NIV) for stabilizing chronic obstructive pulmonary disease during exacerbation. Methods In this randomized clinical trial at Masih‐Daneshvari hospital, between July 2019 and Oct 2019, 30 exacerbated‐COPD‐patient with PaCO2 64.58 ± 11.61 mm Hg, Respiratory Rate 24.43 ± 2.75, and PH 7.31 ± 0.02 were divided into two groups, N = 15. By a simple randomized allocation, patients receive either NIV or HFT for 1 hour, and following a washout period of 30 minutes, they switched to the other treatment option. Arterial Blood Gas Parameters, as well as Respiratory Rate (RR), Dyspnea Score, Heart Rate (HR), and Oxygen Saturation (SO2), were compared before and after the intervention and between groups. Results Baseline patient characteristics were similar in the two groups. Pre and post‐analysis revealed that in both groups, all improved significantly. After the first period, there was no difference in all parameters between groups except for SO2 which was significantly higher in HFT (%92.1 ± 1) than that of NIV (%89 ± 1), P = .001. Likewise, following the washout period, patients in HFT and NIV had a dyspnea score of 1.93 ± 0.7 and 2.73 ± 0.9, respectively, P = .01. No carryover‐effect and was observed but the period effect was significant for some outcomes. A significant improvement in SO2 and HR was observed by HFT according to treatment effect by combining two periods’ results. During the study, no side effects were reported. Conclusion In this short‐term study HFT appears feasible for patients with COPD exacerbation to reduce dyspnea score and improve respiratory distress.

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Noninvasive Mechanical Ventilation

Cited by 6 publications

References 19 publications

Limitations of care and comorbidities are associated with increased mortality in patients treated with non-invasive ventilation: A retrospective observational study in a single-center ICU.

Limitations of care and comorbidities are associated with increased mortality in patients treated with non-invasive ventilation: A retrospective observational study in a single-center ICU.

Monitoring Practical Options: Pharmacology and Noninvasive Mechanical Ventilation

Comparison of high‐flow oxygenation with noninvasive ventilation in COPD exacerbation: A crossover clinical trial

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