Noninvasive monitoring of bone regeneration using NaYF4: Yb3+, Er3+ upconversion hollow microtubes supporting PLGA-PEG-PLGA hydrogel

Xu, Jianxiong; Feng, Yu; Wu, Yangqing; Li, Yanjun; Ouyang, Min; Zhang, Xiping; Wang, Yong; Wang, Yangyun; Xu, Ling

doi:10.1016/j.reactfunctpolym.2019.104333

Cited by 26 publications

(9 citation statements)

References 58 publications

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“…However, excessive Trp may produce a toxic waste in the brain, causing delusions and hallucinations [2]. In addition, it is thought to be a possible cause of schizophrenia in humans who cannot metabolize it properly [3][4][5]. Because of this clinical background, a convenient quantitative method for Trp is expected to bring many medical benefits.…”

Section: Introductionmentioning

confidence: 99%

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Liu

Feng

et al. 2020

Nanomaterials

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In this paper, an electrochemical method for the measurement of tryptophan (Trp) was developed based on a glassy carbon electrode modified with polyvinylpyrrolidonefunctionalized graphene (PVP-GR)/glassy carbon electrode (GCE). In 0.1 M phosphate buffer solution (PBS, pH = 2.2), compared with bare GCE, PVP/GCE, and GR/GCE, the oxidation peak current of Trp increased dramatically at PVP-GR/GCE. The oxidation mechanism of Trp on the PVP-GR/GCE was discussed and the experimental conditions were optimized. Under the best experimental conditions, the oxidation peak current of Trp was proportional to its concentration in the range of 0.06 µM–10.0 µM and 10.0–100.0 µM, and the limit of detection (LOD) was 0.01 µM (S/N = 3). The target modified electrode with excellent repeatability, stability and selectivity, was successfully applied to detectTrp in drugs and biological samples.

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Section: Introductionmentioning

confidence: 99%

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Liu

Feng

et al. 2020

Nanomaterials

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“…The incorporation of micro-to-nano fibers into tissue engineered scaffolds has been widely studied in the past decades. For example, Xu et al prepared poly (lactic-co-glycolic acid) based triblock copolymer microtubes for noninvasive monitoring of bone regeneration [ 37 ]. The microtube embedded hydrogel possessed an ideal sustained drug release property.…”

Section: Discussionmentioning

confidence: 99%

Fabrication of Nanopores Polylactic Acid Microtubes by Core-Sheath Electrospinning for Capillary Vascularization

2021

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There has been substantial progress in tissue engineering of biological substitutes for medical applications. One of the major challenges in development of complex tissues is the difficulty of creating vascular networks for engineered constructs. The diameter of current artificial vascular channels is usually at millimeter or submillimeter level, while human capillaries are about 5 to 10 µm in diameter. In this paper, a novel core-sheath electrospinning process was adopted to fabricate nanoporous microtubes to mimic the structure of fenestrated capillary vessels. A mixture of polylactic acid (PLA) and polyethylene glycol (PEO) was used as the sheath solution and PEO was used as the core solution. The microtubes were observed under a scanning electron microscope and the images were analyzed by ImageJ. The diameter of the microtubes ranged from 1–8 microns. The diameter of the nanopores ranged from 100 to 800 nm. The statistical analysis showed that the microtube diameter was significantly influenced by the PEO ratio in the sheath solution, pump rate, and the viscosity gradient between the sheath and the core solution. The electrospun microtubes with nanoscale pores highly resemble human fenestrated capillaries. Therefore, the nanoporous microtubes have great potential to support vascularization in engineered tissues.

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“…It is a relatively environmentally‐friendly method that can react in a water‐based environment at a relatively low temperature (160 to 220 °C). It is an effective and simple method to prepare inorganic materials with various controllable size and structure, such as sphere (Chen et al., 2019), hexagonal (Wu et al., 2019), rod (Reyes Miranda et al., 2019), micro‐octahedrons (Ray et al., 2019), prismatic microtubes (Xu et al., 2019), and nanofibers (Wei et al., 2019). So far, scientists have successfully synthesized a number of UCNPs via this method.…”

Section: Rational Design Strategy To Construct Upconversion‐based Sen...mentioning

confidence: 99%

Lanthanide ion (Ln³⁺)‐based upconversion sensor for quantification of food contaminants: A review

Rong

Hassan

Ouyang

et al. 2021

Comp Rev Food Sci Food Safe

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The food safety issue has gradually become the focus of attention in modern society. The presence of food contaminants poses a threat to human health and there are a number of interesting researches on the detection of food contaminants. Upconversion nanoparticles (UCNPs) are superior to other fluorescence materials, considering the benefits of large anti‐Stokes shifts, high chemical stability, non‐autofluorescence, good light penetration ability, and low toxicity. These properties render UCNPs promising candidates as luminescent labels in biodetection, which provides opportunities as a sensitive, accurate, and rapid detection method. This paper intended to review the research progress of food contaminants detection by UCNPs‐based sensors. We have proposed the key criteria for UCNPs in the detection of food contaminants. Additionally, it highlighted the construction process of the UCNPs‐based sensors, which includes the synthesis and modification of UCNPs, selection of the recognition elements, and consideration of the detection principle. Moreover, six kinds of food contaminants detected by UCNPs technology in the past 5 years have been summarized and discussed fairly. Last but not least, it is outlined that UCNPs have great potential to be applied in food safety detection and threw new insight into the challenges ahead.

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Noninvasive monitoring of bone regeneration using NaYF4: Yb3+, Er3+ upconversion hollow microtubes supporting PLGA-PEG-PLGA hydrogel

Cited by 26 publications

References 58 publications

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Fabrication of Nanopores Polylactic Acid Microtubes by Core-Sheath Electrospinning for Capillary Vascularization

Lanthanide ion (Ln³⁺)‐based upconversion sensor for quantification of food contaminants: A review

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Noninvasive monitoring of bone regeneration using NaYF4: Yb3+, Er3+ upconversion hollow microtubes supporting PLGA-PEG-PLGA hydrogel

Cited by 26 publications

References 58 publications

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Fabrication of Nanopores Polylactic Acid Microtubes by Core-Sheath Electrospinning for Capillary Vascularization

Lanthanide ion (Ln3+)‐based upconversion sensor for quantification of food contaminants: A review

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Lanthanide ion (Ln³⁺)‐based upconversion sensor for quantification of food contaminants: A review