Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging

Sun, Jing Ping; Popović, Zoran B.; Greenberg, Neil L.; Xu, Xiao Fang; Asher, Craig R.; Stewart, William J.; Thomas, James D.

doi:10.1016/j.echo.2003.10.001

Cited by 159 publications

(118 citation statements)

References 22 publications

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“…Although strain is a local parameter, we excluded LV walls showing positive strain and added peak systolic velocity with concomitant negative strain as a representative value for LC by DTI. According to previous reports, normal values of peak systolic velocity for basal segments of 4 different LV walls in a middle-aged population range from 5.97 to 6.59 cm/s 27,28 ; LC by DTI in healthy control subjects should be higher than 20 cm/s, which is significantly higher than that in our patients with advanced heart failure (7.5 Ϯ 3.9 cm/s).…”

Section: Dti In Heart Failurementioning

confidence: 45%

“…DTI is unique, as it provides a useful clinical tool for quantification of regional myocardial function and myocardial characteriza- tion. 14,24 DTI has been extensively used especially for quantification of LC, [25][26][27][28] which is accepted as an important component of the systolic performance of the LV. One of the main findings of the current study is that the pattern of LC assessed by DTI was variable in patients with severe LV dysfunction.…”

Section: Dti In Heart Failurementioning

confidence: 99%

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Usefulness of Ventricular Longitudinal Contractility Assessed by Doppler Tissue Imaging in the Prediction of Reverse Remodeling in Patients with Severe Left Ventricular Systolic Dysfunction

Kang

Song

et al. 2006

Journal of the American Society of Echocardiography

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Section: Dti In Heart Failurementioning

confidence: 45%

Section: Dti In Heart Failurementioning

confidence: 99%

Usefulness of Ventricular Longitudinal Contractility Assessed by Doppler Tissue Imaging in the Prediction of Reverse Remodeling in Patients with Severe Left Ventricular Systolic Dysfunction

Kang

Song

et al. 2006

Journal of the American Society of Echocardiography

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“…In our study, age had a statistically significant difference, because essential systemic arterial hypertension is present in patients in the fourth decade of life. The influence of age on strain is still controversial, some studies described reduced strain with increasing age, and others found no correlation between strains and age [10][11][12].…”

Section: Discussionmentioning

confidence: 99%

Mechanical Deformation in Patients with Systemic Arterial Hypertension

Avendaño-Pérez¹,

Soto²,

Ávila-Vanzzini³

et al. 2017

J Hypertens

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IntroductionHypertension is one of the most important healthy problems, and the prevalence is of around 20% of the population (variable in different regions of the world), and the hypertension is one of the most important risk factor for cardiovascular diseases, which are the leading causes of death in developed countries [1,2]. Both elevation of systolic pressure and diastolic blood pressure shows a continuous relationship with cardiovascular risk of stroke, coronary heart disease, heart failure, renal failure and peripheral arterial disease [3].Hypertension can cause left ventricular hypertrophy and hyperplasia of the smooth muscle cells and increased production of collagen and elastin tissue. Hypertension represents an increase in cardiac afterload and the compensatory mechanism of is the development of left ventricular concentric hypertrophy. However, unlike hypertrophy which occurs in athletes, the hypertrophy in hypertensive patients occurs with an increase of collagen tissue production, a fact that in the long term leads to left ventricular diastolic dysfunction and secondarily atrial dysfunction by increasing filling pressures predisposing to atrial fibrillation, and in advanced stages systolic dysfunction with dilatation of the cavity and the appearance of heart failure and ventricular arrhythmias [4]. In addition, hypertrophy of the ventricular wall increases the oxygen myocardial demands, which together with the increase incidence of coronary lesions favour myocardial ischemia [5].Several studies have found heterogeneous systolic alterations of the left ventricle (in the longitudinal, radial, and circumferential directions) in diverse clinical settings such as diabetes, hypertension, left ventricle hypertrophy, coronary artery disease, and heart failure [4,6]. The main aim of our study was focused in the assessment of left ventricular mechanical deformation in 20 patients with systemic arterial hypertension and 21 healthy controls to establish the differences in the left ventricular mechanical deformation. Materials and MethodsBetween March 2016 and February 2017, a comparative, observational, prospective, descriptive and analytical study was carried out in 41 subjects. The patients were evaluated consecutively in the Out-patients Clinic, National Institute of Cardiology "Ignacio Chávez". Twenty patients had systemic hypertension and 21 correspond to healthy controls. All participants signed the informed consent. Inclusion criteriaPatients older than 18 years NYHA functional class I/II with a diagnosis of systemic hypertension who had not had any prior surgical or interventional procedure and also patients without valvular or myocardial lesion. AbstractBackground: Systemic arterial hypertension represents the mayor risk factor for several cardiovascular diseases. In a large number of patients it affects the left ventricle by a compensating hypertrophy and posteriorly when this mechanism is insufficient, it leads to heart failure and therefore the patient requires regular echocardiographic monitoring. ...

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“…However, the longitudinal myocardial contractility in early systole is impaired with increased age, even in healthy individuals [16]. Recently, Sun et al [17] demonstrated that the myocardial velocities and strain rate showed a significant dependence on age, whereas displacement and peak systolic strain measures were less affected. Edvardsen et al [18] found that longitudinal myocardial Doppler velocities decreased progressively from the base to the apex of the LV wall, whereas myocardial strain rates and strains were uniform in all segments.…”

Section: Discussionmentioning

confidence: 99%

Regional Myocardial Systolic Function Assessed by Strain Tissue Doppler Imaging in Patients With Isolated Noncompaction of Left Ventricular Myocardium: A Study of Two Cases

et al. 2005

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Noncompacted myocardium has been previously described as the presence of persistent intramyocardial sinusoids. However, the latter is associated with congenital obstructive lesions of the left or right ventricular outflow tract, such as pulmonary atresia with intact ventricular septum [1]. In such patients, regression of the embryogenic sinusoid is impaired during ontogenesis by ventricular pressure overload, resulting in deep recesses that communicate with both the ventricular cavity and the coronary artery system [2,3].By contrast, isolated noncompaction of the left ventricular myocardium (INVM) is an idiopathic cardiomyopathy characterized by an altered structure of the myocardial wall as a result of intrauterine arrest of compaction of the myocardial fibers in the absence of any coexisting congenital lesion [4]. There is continuity between the left ventricular (LV) cavity and the deep intertrabecular recesses that are filled with blood from the ventricular cavity without evidence of communication to the epicardial coronary artery system [5,6]. AbstractIsolated noncompaction of the left ventricular myocardium (INVM) is associated with a high incidence of heart failure.However, it is difficult to determine accurately left ventricular (LV) systolic function because of the trabeculated ventricles. The purpose of this study was to clarify whether strain imaging could detect regional myocardial systolic function in 2 patients with INVM. We recorded myocardial strain profiles at the basal, mid-, and apical portions of the LV free wall and ventricular septum (VS) in the apical LV long-axis view. Case 1 (15-year-old male) was referred to our hospital because of ECG abnormalities. Case 2 (83-year-old female) was admitted to our hospital for congestive heart failure.Two-dimensional echocardiography in both patients showed numerous prominent trabeculations and deep intertrabecular recesses at the apex of the LV wall. Because of the trabeculations, it was difficult to determine accurately LV ejection fraction by 2-dimensional echocardiography. The percent fractional shortening of the LV (%FS) in both cases was within a normal range. However, the peak systolic strains at the apical, mid-, and basal portions of the LV free wall were lower in Case 2 (-12, -12, and -11%, respectively) than in Case 1 (-33, -37, and -37%, respectively). The peak systolic strains at the apical, mid-, and basal portions of the VS were also lower in Case 2 (-11, -16, and -11%, respectively) than in Case 1 (-27, -27, and -29%, respectively). We conclude that strain measurements are useful for evaluating regional myocardial systolic function in patients with INVM. (J Echocardiogr 2005; 3: 40-45) Key words: isolated noncompaction of the left ventricular myocardium, strain imaging, regional myocardial systolic function

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Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging

Cited by 159 publications

References 22 publications

Usefulness of Ventricular Longitudinal Contractility Assessed by Doppler Tissue Imaging in the Prediction of Reverse Remodeling in Patients with Severe Left Ventricular Systolic Dysfunction

Usefulness of Ventricular Longitudinal Contractility Assessed by Doppler Tissue Imaging in the Prediction of Reverse Remodeling in Patients with Severe Left Ventricular Systolic Dysfunction

Mechanical Deformation in Patients with Systemic Arterial Hypertension

Regional Myocardial Systolic Function Assessed by Strain Tissue Doppler Imaging in Patients With Isolated Noncompaction of Left Ventricular Myocardium: A Study of Two Cases

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