Noninvasive Techniques for the Measurement of Isovolumetric Bladder Pressure

Blake, Christopher; Abrams, Paul

doi:10.1097/01.ju.0000102685.44036.b9

Cited by 29 publications

(15 citation statements)

References 32 publications

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“…Thus, preoperative appraisal of detrusor contractile function is of great importance before applying invasive measures to relieve BOO such as transurethral resection of prostate. Currently, invasive urodynamic investigation remains the cornerstone in judging and quantifying the detrusor contractibility preoperatively [3,4,12] .…”

Section: Discussionmentioning

confidence: 99%

“…BOO-induced impairment on detrusor contractibility is a major factor that depresses the evacuation ability of the bladder [2] . Presently, the detrusor pressure at the maximum of urine flow rate obtained from the urodynamic pressure flow study still remains the standard criterion in quantifying the detrusor contractibility after BOO [3,4] . However, these studies are associated with a number of disadvantages: they are time-consuming, expensive and invasive, and entail the risk of urinary tract infection and some morbidity for the patient.…”

Section: Introductionmentioning

confidence: 99%

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Alterations of Urine TGF-β1 and bFGF following Bladder Outlet Obstruction: A Predictor for Detrusor Contractibility?

Shi

Zhu²,

Laudon³

et al. 2009

Urol Int

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Objectives: To investigate the alterations of urine transforming growth factor-β1 (TGF-β1) and basic fibroblast growth factor (bFGF) following bladder outlet obstruction (BOO) in rats and to determine their correlation with the impaired detrusor contractibility. Methods: Wistar rats were divided into control, 2-week BOO 6-week and BOO groups. Impaired detrusor contractibility was quantified by measuring detrusor contraction force (DCF) of detrusor strip stimulated by carbachol. The enzyme-linked immunosorbent assay method was used to determine the urine levels of the 2 factors. Correlation analysis was conducted between DCF and urine levels of the 2 factors to see if there was an association between them after BOO. Results: DCF was found to be significantly lower in the 6-week BOO group than in the 2-week BOO and control groups. There is no significant difference regarding urine TGF-β1 between the 2-week BOO and control groups (p > 0.05). Urine TGF-β1 level in the 6-week BOO group was significantly higher than in the 2-week BOO (p < 0.05) and control groups (p < 0.05). There existed a negative correlation between DCF and urine TGF-β1 (p < 0.05). Conclusions: In an animal model, our results have suggested the potential role of urine TGF-β1 as a noninvasive biomarker to predict detrusor contractibility after BOO.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Alterations of Urine TGF-β1 and bFGF following Bladder Outlet Obstruction: A Predictor for Detrusor Contractibility?

Shi

Zhu²,

Laudon³

et al. 2009

Urol Int

View full text Add to dashboard Cite

show abstract

“…The results are fair but yield limited information. Furthermore, the procedure restricts patient movement and is considered slightly uncomfortable [8,9]. An invasive approach for long term bladder pressure monitoring has been reported in Ref.…”

Section: Different Approaches To Bladder Pressure Measurementsmentioning

confidence: 99%

“…This protection has to serve a dual purpose: the electronics must be shielded from the harsh environment inside the bladder cavity. Vice versa, the bladder must be protected from (3), Capacitance-to-digital converter (4), pressure sensor (5), reed switch (6) and D-Flip-flop (7) mounted on a double-sided Kapton foil (8), and embedded into silicone (9). The total size is 40 mm in length and ∅5 mm.…”

Section: The Bladderpill Designmentioning

confidence: 99%

The BladderPill: An in-body system logging bladder pressure

Jourand

Puers

2010

Sensors and Actuators A: Physical

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“…Blake and Abrams [13] reviewed the noninvasive techniques for the measurement of isovolumetric bladder pressure (P det.iso ). Two of these techniques involve the noninvasive measurement of P det.…”

Section: Discussionmentioning

confidence: 99%

Catheterized Uroflowmetry as a Noninvasive Test for Detrusor Acontractility

Eğilmez

Gören²

2014

Urol Int

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Objective: To evaluate the efficacy of uroflowmetry performed through an indwelling catheter on the differential diagnosis of detrusor acontractility. Patients and Methods: 50 men aged between 51 and 85 years (mean 66 years) presenting to the outpatient urology department with indwelling catheters due to urinary retention were included in the study. In the supine position, 300 ml of saline was instilled into the bladder and the catheter was blocked; with the patient standing by the flowmeter, the catheter was opened, allowing the patient to void through the catheter. The evaluation continued with a cystometry and pressure-flow study (PFS). The patients were separated into two groups according to the results of the PFS - group 1 with positive detrusor pressure and group 2 with negative detrusor pressure (detrusor acontractility) - and the catheterized uroflow and PFS data were compared. Results: Statistical significance was seen between detrusor acontractility and peak flow rate (Q_max) on catheterized uroflow when Q_max <10 ml/s was taken as a threshold value (p = 0). Conclusion: A quick, noninvasive and inexpensive means of assessing lower urinary tract function would improve the management of men needing PFS. This study reveals that catheterized uroflow is a very easy and useful test if the question is whether the bladder is acontractile or not.

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Noninvasive Techniques for the Measurement of Isovolumetric Bladder Pressure

Cited by 29 publications

References 32 publications

Alterations of Urine TGF-β1 and bFGF following Bladder Outlet Obstruction: A Predictor for Detrusor Contractibility?

Alterations of Urine TGF-β1 and bFGF following Bladder Outlet Obstruction: A Predictor for Detrusor Contractibility?

The BladderPill: An in-body system logging bladder pressure

Catheterized Uroflowmetry as a Noninvasive Test for Detrusor Acontractility

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