The aim of the present research is to investigate the nonlinear dynamic and forced vibration of a composite sandwich panel embedded with piezoelectric layers under thermo-harmonic loading. The panel consists of a double-U auxetic honeycomb core made of aluminum alloy and graphene platelet reinforced composite (GPLRC) skins at the top and bottom surfaces. According to Gibson’s formula, the effective material properties of facing sheets and double-V auxetic core are considered. The nonlinear equations are obtained by applying Hamilton’s principles via von Karman’s nonlinear theory and higher-order shear deformation theory (HSDT). The governing equations of motion are solved by employing the differential quadrature method (DQM) and homotopy perturbation method, respectively. The accuracy of the current results has been verified by comparison with others in the literature. Finally, the influence of different parameters such as applied voltage, magnetic potential, temperature rise, different boundary conditions, and geometric parameters of core on the nonlinear frequency-amplitude response of cylindrical panels are analyzed. The numerical results show negative effect of temperature increment, positive influence of ratio of thickness to inclined length, core thickness, amplitudes of segments, considerable effect of the magnetic potential as well as small effect of applied voltage on the nonlinear vibration of sandwich panel. Finally, the important findings of this research indicate that the magnetic potential, amplitude segment, and length to inclined cell rib length have significant effects on nonlinear dynamic deflection and frequencies-amplitude response. Based on the results of this article, designers can develop different parts of aircraft.