This study aims at analysing the jet-like acoustic streaming generated under low-frequency and high-power ultrasound irradiation and comparing it with fluid streaming generated by traditional mechanical mixing. The main characteristics of fluid flow, which include radial, axial and tangential terms of velocity and their effects on fluid flow pattern, pressure distribution, axial mixing time and turbulence intensity were considered at different power inputs. Both 3D CFD simulation and Particle Image Velocimetry (PIV) were used in this study. The CFD results indicated that the jet-like acoustic streaming reached the velocity magnitude of 145 cm/s at 400 W, which reduced the mixing time to 1.38 s. However, the minimum mixing time of 3.18 s corresponding to the impeller rotational speed of 800 RPM was observed for mechanical stirring. A uniform axial flow pattern was generated under ultrasound irradiation whereas the tangential flow pattern was more prominent in the stirred vessel. Besides, the highest turbulence was observed in the vicinity of the ultrasound transducer and impeller with the values of 138% and 82% for the ultrasonicator and stirred vessel, respectively. The predicted fluid flow pattern under ultrasound irradiation was in a reasonable agreement with that obtained from PIV, with a reasonable accuracy.