The global solutions with large initial data for the isothermal compressible fluid models of Korteweg type have been studied by many authors in recent years. However, little is known of global large solutions to the nonisothermal compressible fluid models of Korteweg type up to now. This paper is devoted to this problem, and we are concerned with the global existence of smooth and non-vacuum solutions with large initial data to the Cauchy problem of the one-dimensional nonisothermal compressible fluid models of Korteweg type. The case when the viscosity coefficient µ(ρ) = ρ α , the capillarity coefficient κ(ρ) = ρ β , and the heat-conductivity coefficientα(θ) = θ λ for some parameters α, β, λ ∈ R is considered. Under some assumptions on α, β and λ, we prove the global existence and time-asymptotic behavior of large solutions around constant states. The proofs are given by the elementary energy method combined with the technique developed by Y. Kanel' [23] and the maximum principle.