2015
DOI: 10.1155/2015/410102
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Nonlinear Time Domain Relation between Respiratory Phase and Timing of the First Heart Sound

Abstract: The previous studies on respiratory physiology have indicated that inspiration and expiration have opposite effects on heart hemodynamics. The basic reason why these opposite hemodynamic changes cause regular timing variations in heart sounds is the heart sound generation mechanism that the acoustic vibration is triggered by heart hemodynamics. It is observed that the timing of the first heart sound has nonlinear relation with respiratory phase; that is, the timing delay with respect to the R-wave increases wi… Show more

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