Abstract-This paper addresses the calibration-free robotic eye-hand coordination in a way other than the conventional image Jacobian matrix approach that has been studied extensively in literature. A nonlinear mapping rather than the linear mapping used in the image Jacobian matrix between the image space and the robotic control space is proposed. This mapping is regarded as the system's unmodeled dynamics expressed in system state equations. An extended state observer is designed first to estimate the unmodeled dynamics as well as the external disturbance of the system. With the estimation results as the compensation, a system controller is designed based on the nonlinear state-error feedback control strategy. Convergence of the extended state observer as well as the overall controller for a typical eye-hand coordination system is proved. Compared with the conventional calibration-free robotic eye-hand coordination with a Jacobian matrix, the proposed controller is independent of specific tasks and system configurations. Thus, a general design procedure is proposed for the calibration-free robotic eye-hand coordination. Simulation and experiment results demonstrate the satisfactory performance and effectiveness of the proposed approach.