Nonmalignant pleural lesions due to environmental exposure to asbestos: a field-based, cross-sectional study

Metintaş, Muzaffer

doi:10.1183/09031936.05.00136404

Cited by 41 publications

(39 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They may reflect a local (pleural) response to asbestos fibre accumulation, and are typically detected in exposed construction workers (39). Plaques indicate consistent exposure to low fibre concentrations (0.19 fibre-years/ml) (40). Other potential pleural responses include lymph node calcification and carcinogenesis (41,42).…”

Section: Risk Indicators --------------------------------------------mentioning

confidence: 99%

Detection of pleural plaques in workers exposed to inhalation of natural fluoro-edenite fibres

et al. 2015

View full text Add to dashboard Cite

Abstract. Fluoro-edenite is a natural mineral species initially isolated in Biancavilla, Sicily. The fibres are similar in size and morphology to certain amphibolic asbestos fibres, the inhalation of which may cause chronic inflammation and cancer. Occupational asbestos exposure is known to be associated with pleural and lung diseases, including pleural plaques. The aim of this study was to report the pleural and lung parenchymal lesions detected by high-resolution computed tomography (HRCT) in a group of construction workers exposed to fluoro-edenite. Information regarding life habits and occupational history was collected from 43 workers enrolled into the study. The participants underwent physical examination, blood analysis, search for uncoated fibres and ferruginous bodies in the sputum, pulmonary function tests, including diffusion capacity for carbon monoxide (TL CO ), and HRCT chest imaging. A general descriptive outcome analysis was also conducted; a prevalence ratio (PR) with 95% confidence interval and a two-tailed test P-value were calculated for pleural plaques using log-binomial regression, measuring plaque size and thickness, and cumulative exposure index (CEI). The mean values of the functional respiratory tests were within the normal range for all participants. A restrictive ventilatory defect was identified in two (5%) subjects and an obstructive ventilatory defect in three (7%) subjects. TL CO was reduced in two additional participants. Fibres were detected in 19 (44%) of subjects. Pleural involvement was documented in 39 (91%) workers, of whom 31 (72%) had bilateral plaques. Calcifications were detected in 25 (58%) of these participants. PR indicated a progressive increase in the risk of developing pleural lesions with rising CEI, i.e. length of exposure. The present findings demonstrate for the first time the presence of pleural plaques in the lungs of subjects exposed to fluoro-edenite fibres, and not to asbestos, through residing in Biancavilla and through their occupation.

show abstract

Section: Risk Indicators --------------------------------------------mentioning

confidence: 99%

Detection of pleural plaques in workers exposed to inhalation of natural fluoro-edenite fibres

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Inhalation of asbestos fibers is known to cause benign/malignant pleural and lung diseases such as malignant mesothelioma, lung cancer, diffuse pleural thickening, pleural plaque, and asbestosis (1)(2)(3)(4). Though there is no treatment for the asbestos-related diseases, they can be prevented by preventing asbestos exposure.…”

Section: Introductionmentioning

confidence: 99%

“…However, it is not easy to control environmental asbestos exposure in rural areas. Asbestos exposure in rural areas is a common in many parts of the world including Turkey, Greece, Cyprus, Corsica, and New Caledonia (1)(2)(3)(4)(5)(6)(7)(8). Villagers living in places with abundant asbestos-contaminated soil learned that this soil, called "white soil" in Turkey, "pö" in New Caledonia, and "luto" in Greece (1,7,8), have some advantageous properties.…”

Section: Introductionmentioning

confidence: 99%

“…The combined population of these 379 villages was estimated to be 158,068 based on data from the Turkish Statistical Institute (9). Previous studies have already demonstrated that benign/malignant pleural and lung diseases such as mesothelioma, lung cancer, diffuse pleural thickening, pleural plaque, and asbestosis due to asbestos are common in Eskişe-hir where intensive asbestos exposure in its rural area exists (1)(2)(3)(4).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Validity and Reliability of Asbestos Knowledge and Awareness Questionnaire for Environmental Asbestos Exposure in Rural Areas

Metintaş¹,

Ak²,

Yılmaz³

et al. 2017

Eurasian J Pulmonol

View full text Add to dashboard Cite

Objective: There is no treatment for asbestos-related diseases, but they can be prevented. One of the first interventions is to improve the knowledge level of people in order to protect people from asbestos and asbestos-related diseases. The present study was conducted to develop a questionnaire for measuring the knowledge and awareness level of asbestos and also assess its validity and reliability in a rural population that is exposed to asbestos environmentally. Methods:A questionnaire, interviewer-administered, that included 37 items was employed on a convenient sample consisting of adult persons who attended a tertiary teaching hospital in Eskişehir where asbestos exposure is widespread in its rural areas. After assessment of validity and reliability of the results, the questionnaire was refined to 19 items and one subscale.Results: A total of 760 participants were included in this study. The mean age of participants was 53.2±15.1 years and 51.6% of them were male. The discrimination and difficulty indices of the asbestos knowledge and awareness questionnaire ranged between 20.0-60.5% and 0.39-0.98, respectively. Cronbach's alpha coefficient was 0.951 for overall items. The median (min-max) and mean (SD) score of the study population were 30 (19-56) and 33.9 (11.9), respectively. The score increased correspondingly with greater knowledge levels. Conclusion:This questionnaire is a practical and easy tool to apply with acceptable reliability and validity on high-risk adults in rural areas with environmental asbestos exposure.

show abstract

“…Compared with the general population, asbestos-related diseases have been found to have higher incidence rates among the population that has been exposed to asbestos [5][6][7]. In this supplement to the Turkish Thoracic Journal, Metintaş et al provide the results of the "Turkey Asbestos Control Strategic Plan."…”

mentioning

confidence: 99%

Elimination of Asbestos-Related Diseases in Turkey Still Has a Long Way to Go

Akgün

2015

Turk Thorac J

View full text Add to dashboard Cite

Nonmalignant pleural lesions due to environmental exposure to asbestos: a field-based, cross-sectional study

Cited by 41 publications

References 34 publications

Detection of pleural plaques in workers exposed to inhalation of natural fluoro-edenite fibres

Detection of pleural plaques in workers exposed to inhalation of natural fluoro-edenite fibres

Validity and Reliability of Asbestos Knowledge and Awareness Questionnaire for Environmental Asbestos Exposure in Rural Areas

Elimination of Asbestos-Related Diseases in Turkey Still Has a Long Way to Go

Contact Info

Product

Resources

About