Cognitive enhancement (CE) agents are those purported to improve or augment aspects of cognition such as working memory, creativity, and executive function in healthy individuals. CE by university students looking to improve their academic performance, particularly through the use of pharmacological agents (or nootropics), has become an area of increasing interest for researchers. However, studies on the prevalence of, and motivations behind, students' CE use at Australian universities are limited. This study aimed to contribute a new sample of prevalence data, as well as corroborate previous qualitative research that has suggested that emotion-focused and avoidant coping styles may make students more susceptible to utilizing CE drugs. A sample of N=633 individuals was recruited to complete the BCognitive Enhancement and Student Lifestyle Survey^online. The key questions of interest concerned students' enhancement drug usage habits, usage motivations, and coping styles. Analyses found that 6.32% of students indicated lifetime use of prescription CE agents for the purposes of study-related enhancement. Furthermore, dysfunctional coping strategies were associated with an increased likelihood of both lifestyle and prescription CE drug use. Findings from this study refine current understandings of enhancement drug use in Australia and are contextualized in regard to potential avenues for on-campus health interventions and regulatory opportunities. In particular, helping students to maintain manageable stress levels through identifying less harmful coping strategies may prove useful.