“…13 Our patient's rash was consistent with an exanthematous drug eruption with a Naranjo score of 6, 14 indicating that vancomycin was most likely the causative agent of the patient's drug eruption. Patients with autoimmune diseases have a high incidence of drug allergy, such as Sjogren's syndrome, systemic lupus erythematosus, and adult-onset Still's disease, 11 additionally DN could be accompanied by Sjogren's syndrome, 4 several autoantibodies were positive in this patient, and connective tissue disease could not be excluded after consultation with the rheumatology department, because the patient had no symptoms, such as the dry mouth and eyes, oral ulcers, joint pain, and photaesthesia, thus he could not be further diagnosed. The relationship between a patient's autoantibody and drug eruptions, DN, or both remains uncertain.…”