Nonoperative management of appendicitis in children

López, Joseph J.; Deans, Katherine J.; Minneci, Peter C.

doi:10.1097/mop.0000000000000487

Cited by 45 publications

(31 citation statements)

References 24 publications

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“…ingestion could be due to dietary fibers such as pectin and mucilage [81], which may slow down the absorption of glucose by increasing the viscosity of food in the gut [86, 87]. Likewise, polysaccharides isolated from O. ficus-indica or O. streptacantha could exert a hypoglycemic effect in diabetic mice [88].…”

Section: Biological and Medical Properties Of Opuntia Spp In Chromentioning

confidence: 99%

Opuntia spp.: Characterization and Benefits in Chronic Diseases

Díaz

Rosa

Héliès-Toussaint

et al. 2017

Oxidative Medicine and Cellular Longevity

112

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Opuntia species have been used for centuries as food resources and in traditional folk medicine for their nutritional properties and their benefit in chronic diseases, particularly diabetes, obesity, cardiovascular diseases, and cancer. These plants are largely distributed in America, Africa, and the Mediterranean basin. Opuntia spp. have great economic potential because they grow in arid and desert areas, and O. ficus-indica, the domesticated O. species, is used as a nutritional and pharmaceutical agent in various dietary and value-added products. Though differences in the phytochemical composition exist between wild and domesticated (O. ficus-indica) Opuntia spp., all Opuntia vegetatives (pear, roots, cladodes, seeds, and juice) exhibit beneficial properties mainly resulting from their high content in antioxidants (flavonoids, ascorbate), pigments (carotenoids, betalains), and phenolic acids. Other phytochemical components (biopeptides, soluble fibers) have been characterized and contribute to the medicinal properties of Opuntia spp. The biological properties of Opuntia spp. have been investigated on cellular and animal models and in clinical trials in humans, allowing characterization and clarification of the protective effect of Opuntia-enriched diets in chronic diseases. This review is an update on the phytochemical composition and biological properties of Opuntia spp. and their potential interest in medicine.

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Section: Biological and Medical Properties Of Opuntia Spp In Chromentioning

confidence: 99%

Opuntia spp.: Characterization and Benefits in Chronic Diseases

Díaz

Rosa

Héliès-Toussaint

et al. 2017

Oxidative Medicine and Cellular Longevity

112

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“…The most common cause of abdominal pain requiring surgical intervention is acute appendicitis. If uncomplicated, it can be managed safely with non‐operative treatment (antibiotic treatment) …”

Section: Introductionmentioning

confidence: 99%

“…Ultrasound can reduce the rates of appendicectomy, with one study finding that increased rates of diagnostic imaging were associated with lower negative appendicectomy results (NARs) for all age and gender subgroups, other than children younger than 5 years . In addition, the efficacy of non‐operative treatment of acute uncomplicated appendicitis has been confirmed . However, many rural and remote areas do not have access to diagnostic imaging services…”

Section: Introductionmentioning

confidence: 99%

“…If uncomplicated, it can be managed safely with non-operative treatment (antibiotic treatment). 1 There is very little Australian literature on the rates of acute appendicitis. From 2017 to 2018, acute appendicitis emergency department presentations equalled 25,880 (1.0% [25,800/ 2,492,756]), with the most common emergency department presentation being for abdominal and pelvic pain (n = 142,666), with 45,938 presentations in the 10-to 19-yearold age group.…”

Section: Introductionmentioning

confidence: 99%

“…9 In addition, the efficacy of non-operative treatment of acute uncomplicated appendicitis has been confirmed. 1 However, many rural and remote areas do not have access to diagnostic imaging services. 4 Point-of-care ultrasound is non-invasive and enables narrowing of the differential diagnoses and, in some instances, definitive diagnosis.…”

Section: Introductionmentioning

confidence: 99%

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Aeromedical retrieval for suspected appendicitis in rural and remote paediatric patients

Harwood¹,

Black²,

Sharma³

et al. 2020

Australas J Ultrason Med

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Introduction The aim of this paper was to describe the characteristics of paediatric patients who underwent an aeromedical retrieval within Australia (gender and Indigenous status) for suspected appendicitis between 1 July 2014 and 30 June 2018 (4 years). By understanding these trends, we hope to further justify the need for point‐of‐care ultrasound training for clinicians working in rural and remote Australia. Method Participants included Royal Flying Doctor Service (RFDS) patients aged 0–18 years (inclusive) who underwent an aeromedical retrieval for suspected appendicitis within Australia. Data were collected and coded on each patient’s inflight working diagnosis, using the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification (ICD‐10‐AM) coding method. A combination of descriptive statistics and chi‐square analyses was used in data analysis, with significance considered at <0.05. Results There were 384 children with a working diagnosis of suspected appendicitis, including 191 (49.7%) males and 193 (50.3%) females, with 133 (34.6%) patients identifying as Aboriginal and/or Torres Strait Islander (hereafter referred to as Indigenous) Australians. The aeromedical retrievals were from rural and remote locations to inner‐regional or metropolitan hospitals, with an average distance flown of 339.0 (SD = 206.4) kilometres. The RFDS most frequently retrieved for acute appendicitis (n = 159; 41.4%), acute abdominal pain (n = 127; 33.1%), and unspecified appendicitis (n = 84; 21.9%). There were non‐significant (P = 0.9) diagnostic differences between genders. Non‐Indigenous patients were overrepresented, compared with Indigenous patients, in relation to a transfer with a diagnosis of acute appendicitis (P = <0.01), whereas Indigenous patients were overrepresented, compared with non‐Indigenous patients, in relation to transfers with diagnoses of acute abdomen pain and unspecified appendicitis (P = <0.01). Conclusion A significant number of paediatric patients are aeromedically retrieved from rural and remote locations with a diagnosis of appendicitis or acute abdominal pain. Future research should consider whether training in abdominal point‐of‐care ultrasound reduces retrievals.

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Non-operative Management of Complicated Appendicitis

Dubina

Lee

2019

Controversies in Pediatric Appendicitis

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Nonoperative management of appendicitis in children

Cited by 45 publications

References 24 publications

Opuntia spp.: Characterization and Benefits in Chronic Diseases

Opuntia spp.: Characterization and Benefits in Chronic Diseases

Aeromedical retrieval for suspected appendicitis in rural and remote paediatric patients

Non-operative Management of Complicated Appendicitis

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