Nonoperative management of delayed splenic rupture in a patient with hemophilia B

Terry, N. Elizabeth; Boswell, William C.

doi:10.1016/j.jpedsurg.2006.05.061

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Noncentral Nervous System Emergent Events1

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Cited by 4 publications

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“…Either may be associated with no apparent antecedent trauma [45]. Modern imaging techniques should readily distinguish between the two entities [43]. In either instance early replacement therapy is essential, even if abdominal surgery is not contemplated immediately [40].…”

Section: Resultsmentioning

confidence: 99%

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Emergency Management of Hemophilia

Hoots¹

2014

Textbook of Hemophilia

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Section: Resultsmentioning

confidence: 99%

“…splenectomy) [41,42] or to repair it (liver, kidney, or bowel wall) [37]. Early infusion of clotting factor may pre-empt the expansion of the hematoma and forestall surgery in emergent circumstances [43].…”

Section: Noncentral Nervous System Emergent Eventsmentioning

confidence: 99%

Emergency Management of Hemophilia

Hoots¹

2014

Textbook of Hemophilia

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“…26 Spontaneous, or apparently so, splenic rupture has been reported in hemophilia A and B. 27,28 Spinal epidural hematomas are extremely rare bleeding manifestations in patients with hemophilia. They usually require a rapid surgical intervention to avoid spinal cord compression with consequent severe neurological sequels.…”

Section: Resultsmentioning

confidence: 99%

Rare and Unusual Bleeding Manifestations in Congenital Bleeding Disorders

Girolami

Vettore

Ruzzon

et al. 2011

Clin Appl Thromb Hemost

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Epistaxis, superficial and deep hematomas, hemarthrosis, gastrointestinal bleeding, hematuria represent the most frequent hemorrhagic events in congenital coagulation disorders. Occasionally, bleeding manifestations occur in unusual sites or are peculiar. A clotting defect may alter the clinical aspect of skin conditions or infections (hemorrhagic scabies or varicella). Hemobilia may occur as a complication of transjugular liver biopsy in hemophilia or Bernard-Soulier syndrome. Hemarthrosis of small joints of feet and hands occur in patients with hemophilia treated with protease inhibitors. Intramedullary hematomas of long bones have been described in α2-plasmin inhibitor or fibrinogen deficiencies. Spleen fracture with consequent hemoperitoneum has been reported in patients with fibrinogen deficiency. Rectus muscle sheath hematoma may occur in patients with factor VII (FVII)or FX deficiency. Acute or subacute intestinal obstruction may be caused by intramural wall hematomas in hemophilia and von Willebrand (vW)-disease. Physicians should always keep in mind that a congenital hemorrhagic disorder may cause bleeding in any tissue of the body and therefore alter the normal clinical features of a given disease.

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Emergency Management of Hemophilia

Hoots

2010

Textbook of Hemophilia

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Nonoperative management of delayed splenic rupture in a patient with hemophilia B

Cited by 4 publications

References 6 publications

Emergency Management of Hemophilia

Emergency Management of Hemophilia

Rare and Unusual Bleeding Manifestations in Congenital Bleeding Disorders

Emergency Management of Hemophilia

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