Nonoperative Management of Scleroderma of the Hand With Tadalafil and Subatmospheric Pressure Wound Therapy: Case Report

Patel, Ronak M.; Nagle, Daniel J.

doi:10.1016/j.jhsa.2011.12.030

Cited by 11 publications

(2 citation statements)

References 11 publications

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“…Amputation had initially been suggested for the 61-year-old patient; however, following medical optimization with tadalafil and 4 months of subatmospheric pressure treatment using a VAC dressing (KCI, San Antonio, Texas, United States) his wounds healed with no evidence of infection and no need for amputation. 38…”

Section: Sclerodermamentioning

confidence: 99%

Topical Negative Pressure Wound Dressing and Its Applications in the Hand—A Review of the Literature

Logan

Scott

Peake

et al. 2022

Journal of Hand and Microsurgery

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The use of topical negative pressure wound therapy (NPWT) has become increasingly popular in the management of complex wounds. There are many theories as to the mechanism of action of NPWT, but the essential components of the various systems remain consistent. There are many attractive potential properties of negative pressure dressings that lend themselves to the management of upper limb injuries. This article explores the technique of negative pressure wound dressing, the theories pertaining to mechanism of action, and the increasingly broad indications described for the use of NPWT in the hand. The literature pertaining to the efficacy of NPWT in general is also discussed.

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Section: Sclerodermamentioning

confidence: 99%

Topical Negative Pressure Wound Dressing and Its Applications in the Hand—A Review of the Literature

Logan

Scott

Peake

et al. 2022

Journal of Hand and Microsurgery

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“…487,488 Case reports indicate that topical negative pressure therapy is effective for treating SSc digital ulcers, ulcers on other parts of the body and gangrene. [489][490][491] One report demonstrated the efficacy of intermittent pneumatic compression on 26 patients with ulcers on their upper limbs, including some with SSc. 492 One case report showed that platelet-rich plasma effectively treated scleroderma skin ulcers.…”

Section: Cq15 What Ointments Effectively Treat Ulcers And/or Gangrene?mentioning

confidence: 99%

Diagnostic criteria, severity classification and guidelines of systemic sclerosis

Asano

Jinnin

Kawaguchi

et al. 2018

The Journal of Dermatology

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Several effective drugs have been identified for the treatment of systemic sclerosis (SSc). However, in advanced cases, not only their effectiveness is reduced but they may be also harmful due to their side-effects. Therefore, early diagnosis and early treatment is most important for the treatment of SSc. We established diagnostic criteria for SSc in 2003 and early diagnostic criteria for SSc in 2011, for the purpose of developing evaluation of each organ in SSc. Moreover, in November 2013, the American College of Rheumatology and the European Rheumatology Association jointly developed new diagnostic criteria for increasing their sensitivity and specificity, so we revised our diagnostic criteria and severity classification of SSc. Furthermore, we have revised the clinical guideline based on the newest evidence. In particular, the clinical guideline was established by clinical questions based on evidence-based medicine according to the New Minds Clinical Practice Guideline Creation Manual (version 1.0). We aimed to make the guideline easy to use and reliable based on the newest evidence, and to present guidance as specific as possible for various clinical problems in treatment of SSc.

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Successful treatment of skin fistulas in systemic sclerosis patients with the combination of topical negative pressure therapy and split-thickness skin grafting

et al. 2013

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Nonoperative Management of Scleroderma of the Hand With Tadalafil and Subatmospheric Pressure Wound Therapy: Case Report

Cited by 11 publications

References 11 publications

Topical Negative Pressure Wound Dressing and Its Applications in the Hand—A Review of the Literature

Topical Negative Pressure Wound Dressing and Its Applications in the Hand—A Review of the Literature

Diagnostic criteria, severity classification and guidelines of systemic sclerosis

Successful treatment of skin fistulas in systemic sclerosis patients with the combination of topical negative pressure therapy and split-thickness skin grafting

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