Nonoperative treatment of acute appendicitis in children

Abeş, Musa; Petik, Bülent; Kazıl, Selçuk

doi:10.1016/j.jpedsurg.2007.03.049

Cited by 111 publications

(103 citation statements)

References 12 publications

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“…Antibiotic therapy probably causes regression of lymphoid hyperplasia because of suppression of bacterial infection and prevents ischemia and bacterial invasion in the early stage of appendicitis. 10 If intravenous antibiotics are administered for less than 5 days, oral antibiotics should be administered for a total period of 7 days. 11 In adults, the common antibiotics used are amoxicillin + clavulanic acid, cephalosporins or fluoroquinolones.…”

Section: Discussionmentioning

confidence: 99%

A Study on Outcome of Conservatively Managed Appendicitis

Sebastian¹,

Sreekumar²,

Othayath³

2018

jebmh

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Section: Discussionmentioning

confidence: 99%

A Study on Outcome of Conservatively Managed Appendicitis

Sebastian¹,

Sreekumar²,

Othayath³

2018

jebmh

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“…They reported an overall complication rate of 8.6% for surgical patients and 10% for patients treated with antibiotics; however, all complications in the antibiotic group developed after a subsequent appendectomy. Abes and colleagues [27] performed a retrospective analysis of patient records to assess the impact of non-operative treatment of acute appendicitis in children and concluded that antibiotics have a role in the management of localized abdominal tenderness. The authors found a statistically significant decrease in appendix size (radiologic imaging) in the antibiotic treatment group.…”

Section: Discussionmentioning

confidence: 99%

Antibiotics-First Strategy versus Appendectomy in the Management of Acute Appendicitis

Kou¹,

Chen²

2017

OALib

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Acute appendicitis is the most common cause of acute abdominal disorders requiring surgery. The mainstay of treatment is an appendectomy for more than 100 years. However, symptoms of acute appendicitis confuse many other conditions making diagnosis a challenge. In addition, as with all operations, postoperative complications exist, including wound infections, intra-abdominal abscesses, ileus and adhesions. For some specific patients (the first trimester of pregnancy or who have contraindications), surgery is not the best choice. So it is important to confirm if antibiotics-first approach is effective and may be used as an alternative treatment for appendectomy.

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“…Bununla birlikte, bu süreç içinde tüm akut apandisit olguları için apendektominin gerekliliği ve aciliyeti hep tartışıl-mıştır (1,(7)(8)(9)(10) . Bundan 10-15 yıl önce tüm akut apandisit olgularında, perforasyona bağlı komplikasyonlardan kaçınmak için olgu gece yarısı da gelse kesinlikle acil ameliyata alınması kabul görürken, Yardeni ve ark.…”

Section: Discussionunclassified

“…Son on yılda, çocuklarda komplike olmayan akut apandisit olgularının antibiyotikle tedavi edilebileceğini ve antibiyotik tedavisinin bir seçenek olarak sunulabileceğini belirten 10'a yakın çalışma yayın-lanmıştır (9,10) . Antibiyotik tedavisinin, %25'i bulan negatif apendektomileri engellediği, apendiksi koruduğu, cerrahi ve anesteziyle ilgili komplikasyonları engellediği belirtilmektedir.…”

Section: Discussionunclassified