We study the scope of local indirect least squares (LILS) methods for nonparametrically estimating average marginal e¤ects of an endogenous cause X on a response Y in triangular structural systems that need not exhibit linearity, separability, or monotonicity in scalar unobservables. One main …nding is negative: in the fully nonseparable case, LILS methods cannot recover the average marginal e¤ect. LILS methods can nevertheless test the hypothesis of no e¤ect in the general nonseparable case. We provide new nonparametric asymptotic theory, treating both the traditional case of observed exogenous instruments Z and the case where one observes only error-laden proxies for Z. Acknowledgement 0.1 We thank Stefan Hoderlein, Xun Lu, Andres Santos, and Suyong Song for helpful comments and suggestions. Any errors are the authors' responsibility. S. M. Schennach acknowledges support from the National Science Foundation via grants SES-0452089 and SES-0752699. This is a revised version of a paper titled "Estimating Average Marginal E¤ ects in Nonseparable Structural Systems." JEL Classi…cation Numbers: C13, C14, C31.