Multidisciplinary Management of Common Bile Duct Stones 2016
DOI: 10.1007/978-3-319-22765-8_17
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Nonprocedural Management of Common Bile Duct Stones

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“…Actually, biliary blockage is thought to reduce human antibacterial defenses, promote immunological dysfunction, and increase small bowel bacterial colonization. Although the specific method is unknown, the retrograde ascent is the way in which germs are thought to enter the biliary system through the duodenum or portal venous blood [5].…”
Section: Discussionmentioning
confidence: 99%
“…Actually, biliary blockage is thought to reduce human antibacterial defenses, promote immunological dysfunction, and increase small bowel bacterial colonization. Although the specific method is unknown, the retrograde ascent is the way in which germs are thought to enter the biliary system through the duodenum or portal venous blood [5].…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, Kialian stated that CBD expansion resulted from decreased hypotonic activity and contractility of the duct. They further suggested that this was mainly due to the characteristic fragmentation of the longitudinal smooth myocyte bands, interspersed connective tissue, and a decrease in the reticular-elastic framework of the duct wall over time [26]. Also, the use of calcium antagonists and nitroglycerine in the ageing population has been suggested to influence contractility and tonicity of the CBD wall, thus contributing to the variations in CBD [11].…”
Section: Discussionmentioning
confidence: 99%