“…In addition to NMD triggering features, NMD‐mediated degradation of mRNAs can respond to growth conditions. It has been shown that regulation of a number of transcripts by NMD depends on environmental conditions (Gaba et al, 2005; Johansson & Jacobson, 2010; M. Peccarelli et al, 2016, 2019). In Saccharomyces cerevisiae and other eukaryotes, three core NMD factors, Upf1p, Upf2p, and Upf3p, are required for the pathway to function.…”