Nonsurgical Fertility Control

Benka, Valerie A.W.

doi:10.1002/9781119380528.ch8

Cited by 1 publication

(1 citation statement)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar zinc gluconate sterilants have been launched in Brazil under the names Infertile® (RhobiPharma Ind. Farm., Hortolândia, SP, BR) ( 339 , 340 ) and Testoblock® (BioRelease Technologies LCC, Birmingham, AL, USA) ( 341–344 ). Overall, this approach has not received a broad market acceptance due to inconsistencies in results and concerns regarding animal welfare.…”

Section: Methods Of Sterilizationmentioning

confidence: 99%

Male animal sterilization: history, current practices, and potential methods for replacing castration

Hess,

Park,

Soto

et al. 2024

Front. Vet. Sci.

View full text Add to dashboard Cite

Sterilization and castration have been synonyms for thousands of years. Making an animal sterile meant to render them incapable of producing offspring. Castration or the physical removal of the testes was discovered to be the most simple but reliable method for managing reproduction and sexual behavior in the male. Today, there continues to be global utilization of castration in domestic animals. More than six hundred million pigs are castrated every year, and surgical removal of testes in dogs and cats is a routine practice in veterinary medicine. However, modern biological research has extended the meaning of sterilization to include methods that spare testis removal and involve a variety of options, from chemical castration and immunocastration to various methods of vasectomy. This review begins with the history of sterilization, showing a direct link between its practice in man and animals. Then, it traces the evolution of concepts for inducing sterility, where research has overlapped with basic studies of reproductive hormones and the discovery of testicular toxicants, some of which serve as sterilizing agents in rodent pests. Finally, the most recent efforts to use the immune system and gene editing to block hormonal stimulation of testis function are discussed. As we respond to the crisis of animal overpopulation and strive for better animal welfare, these novel methods provide optimism for replacing surgical castration in some species.

show abstract

Section: Methods Of Sterilizationmentioning

confidence: 99%