Nonsurgical Management of the Neurogenic Bladder in Children

Kryger, John V.

doi:10.1100/tsw.2008.146

Cited by 5 publications

(4 citation statements)

References 37 publications

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“…These patients are often treated with clean intermittent catheterization (CIC) to decrease the risk of unsafe bladder pressures and ensure adequate bladder emptying. Patients who perform CIC for neurogenic bladder frequently develop chronic bacterial colonization, also known as asymptomatic bacteriuria [ 1 , 2 ]. Chronic asymptomatic colonization does not require antibiotic treatment.…”

Section: Introductionmentioning

confidence: 99%

Genetic Evaluation ofE. coliStrains Isolated from Asymptomatic Children with Neurogenic Bladders

Kryger

Burleigh

Christensen

et al. 2015

International Journal of Chronic Diseases

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This study was conducted to describe the genetic profiles of E. coli that colonize asymptomatic pediatric neurogenic bladders. E. coli was isolated from 25 of 80 urine samples. Patients were excluded if they presented with symptomatic urinary tract infection or received treatment with antibiotics in the preceding three months. Multiplex PCR was performed to determine E. coli phylotype (A, B1, B2, and D) and the presence of seven pathogenicity islands (PAIs) and 10 virulence factors (VFs). E. coli strains were predominantly of the B1 and B2 phylotype, with few strains in the A or D phylotype. The PAIs IV536, ICFT073, and IICFT073 had the highest prevalence: 76%, 64%, and 48%, respectively. The PAIs II536, IJ96, and IIJ96 were less prevalent: 28%, 20%, and 24%, respectively. The most prevalent VF was vat (40%), while the least prevalent VFs were sfa (8%) and iha (12%). None of the strains carried the VF fyuA, which is very common in uropathogenic E. coli (UPEC). The genetic profiles of E. coli in this cohort seem to be more similar to UPEC than to commensal E. coli. However, they appear to have reduced virulence potential that allows them to colonize asymptomatically.

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Section: Introductionmentioning

confidence: 99%

Genetic Evaluation ofE. coliStrains Isolated from Asymptomatic Children with Neurogenic Bladders

Kryger

Burleigh

Christensen

et al. 2015

International Journal of Chronic Diseases

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“…Concordando com Molin et al, (2018), Kryger (2008) estudou o gerenciamento não cirúrgico da bexiga neurogênica em crianças, os resultados mostraram que o manejo da (BN) evoluiu nos últimos 30 anos bastante. Para o autor com gerenciamento adequado, a incidência de insuficiência renal é rara.…”

Section: Resultsunclassified

Abordagem da fisioterapia pediátrica na bexiga neurogênica

Feitosa¹,

Costa

Meneses

et al. 2022

RSD

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O presente artigo tem como objetivo investigar através da literatura como a fisioterapia pediátrica pode auxiliar no tratamento da bexiga neurogênica, bem como o melhor tratamento fisioterapêutico para pacientes acometidos por essa síndrome e como a fisioterapia pode ajudar na qualidade de vida de portadores da bexiga neurogênica. Para tanto, trata-se de um Estudo do tipo Revisão Integrativa da Literatura. Para levantamento dos artigos foram utilizadas as seguintes bases: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Medical Literature Analysis and Retrieval Sistem on-line (Medline) e Scientific Electronic Library Online (SCIELO). Foram utilizados, para busca dos artigos, os seguintes descritores e suas combinações nas línguas portuguesa, espanhola e inglesa: “Fisioterapia”, “Incontinência Urinária”, “Bexiga Neurogênica”. A princípio, a busca pelos descritores foi dada individualmente, utilizando-se posteriormente o cruzamento a partir do operador booleano “and”. Os estudos analisados mostraram que os recursos fisioterapêuticos como uroterapia, terapia comportamental, eletroestimulação transcutânea parassacral e tibial posterior, podem ser usados no tratamento de Bexiga Neurológica, contudo é necessário também o tratamento interdisciplinar para diminuição dos sintomas e sinais, nos transtornos físicos e emocionais, na melhora do convívio social e principalmente na melhora na qualidade de vida dessas crianças.

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“…The most frequent causes of reduced functional or anatomical BC in children are neurogenic dysfunction (NVD), posterior urethral valves (PUVs), and bladder exstrophy (BE). When more conservative methods ( 1 ) such as medications or injection of Botulinum toxin fail, surgical bladder augmentation is needed to achieve continence and prevent or correct hydronephrosis.…”

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Alternatives to Conventional Enterocystoplasty in Children: A Critical Review of Urodynamic Outcomes

González¹,

Ludwikowski²

2013

Front. Pediatr.

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Alternatives to conventional enterocystoplasty have been developed in order to avoid the most common complications derived from contact of the urine with intestinal mucosa. In this article critically we review the literature on the topics: ureterocystoplasty, detrusorectomy, detrusorotomy, seromuscular gastroenterocystoplasty, use of off the shelf biomaterials, and bladder augmentation by bioengineering. Recognizing the difficulty of deciding when a child with a history of posterior urethral valves requires and augmentation and that the development of a large megaureter in cases of neurogenic dysfunction represents a failure of initial treatment, we conclude that ureterocystoplasty can be useful in selected cases when a large dilated ureter is available. Seromuscular colocystoplasty lined with urothelium (SCLU) has been urodynamically effective in several series when the outlet resistance is high and no additional intravesical procedures are necessary. Seromuscular gastrocystoplasty lined with urothelium seems to offer no distinct advantages and involves a much more involved operation. The use of seromuscular segments without urothelial preservation, with or without the use of an intravesical balloon has been reported as successful in two centers but strict urodynamic evidence of its effectiveness is lacking. The published evidence argues strongly against the use of detrusorectomy or detrusorotomy alone because of the lack of significant urodynamic benefits. Two recent reports discourage the use of small intestinal submucosa patches because of a high failure rate. Finally, research into the development of a bioengineered bladder constructed with cell harvested from the same patient continues but is fraught with technical and conceptual problems. In conclusion of the methods reviewed, only ureterocystoplasty and SCLU have been proven urodynamically effective and reproducible.

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Nonsurgical Management of the Neurogenic Bladder in Children

Cited by 5 publications

References 37 publications

Genetic Evaluation ofE. coliStrains Isolated from Asymptomatic Children with Neurogenic Bladders

Genetic Evaluation ofE. coliStrains Isolated from Asymptomatic Children with Neurogenic Bladders

Abordagem da fisioterapia pediátrica na bexiga neurogênica

Alternatives to Conventional Enterocystoplasty in Children: A Critical Review of Urodynamic Outcomes

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