Nonsurgical Treatment of Peri-Implantitis: Case Series

Diachkova, Ekaterina; Corbella, Stefano; Taschieri, Silvio; Тарасенко, С. В.

doi:10.3390/dj8030078

Cited by 5 publications

(5 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mensi et al reported improvements in PPD and BOP using a Multiple Anti-Infective Non-Surgical Treatment (MAINST) protocol that consisted of two treatments, each executed in two consecutive weeks, based on air polishing, ultrasonic, manual debridement, chlorhexidine rinse, and a final pocket filling with doxycycline gel 14% (Ligosan ® Kulzer Gmbh, Hanau, Germany) [ 56 ]. The same results were also reported in Moura et al and Diachova et al, where improvements in PD [ 57 , 58 ] and BOP [ 58 ] were registered after using local doxycycline. These findings confirmed Butcher et al (2004), who demonstrated a significant improvement in peri-implant disease after applying doxycycline as a local antibiotic [ 39 ].…”

Section: Discussionsupporting

confidence: 86%

Local/Topical Antibiotics for Peri-Implantitis Treatment: A Systematic Review

et al. 2021

View full text Add to dashboard Cite

Most studies indicate that the mechanical removal of the bacterial biofilm from the implant surface is the central goal of peri-implantitis therapy. However, controversial results in the treatment of peri-implantitis have led to the consideration of additional strategies that include surgical approaches and chemical adjuvants. Local/topical antibiotics, such as minocycline, azithromycin, tetracycline, amoxicillin, doxycycline, and metronidazole, may improve the efficacy of the definitive treatment of the disease, but the lack of conclusive findings prevents their use in clinical practice. This systematic review aimed to evaluate the effect of local/topical antibiotics for peri-implantitis treatment. Randomised controlled studies (RCT) on patients with peri-implantitis and comparing the efficacy of local/topical antibiotics vs. placebo or mechanical debridement were included. A systematic search strategy was carried out using three registered databases (PubMed, Web of Science, and Scopus). RoB2 was used to assess risk of bias. Five RCTs were identified (n = 250 patients and 333 implants). Contrast results emerged among the included studies, and a high heterogeneity level was observed. Risk of bias revealed some concerns for three studies out of five, while one study was judged at high risk. Only one study analysed the limitations of its findings. Overall, local antibiotic use can be considered a valid approach in the treatment of peri-implantitis. Therefore, future long-term clinical trials with standardised protocols and antibiotics with similar biological activity profiles should be tested to achieve a valid and definitive conclusion.

show abstract

Section: Discussionsupporting

confidence: 86%

Local/Topical Antibiotics for Peri-Implantitis Treatment: A Systematic Review

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The results of the study demonstrated the safety of such early disposal of the stent, which corresponds to the results of the works of other authors. In two comparative studies, the authors demonstrated the safety and effectiveness of stent removal one week after surgery [23][24][25][26].…”

Section: Discussionmentioning

confidence: 99%

Outcomes of laparoscopic pyeloplasty and impact of an enhanced recovery protocol

Beloborodov,

Vorobev,

Kalyagin

et al. 2024

ELECTRON J GEN MED

View full text Add to dashboard Cite

Purpose: The study aims to analyze the enhanced recovery protocol’s (ERP) effectiveness in a comparative study of elective surgeries for ureteropelvic junction obstruction (UPJO). Methods: The prospective study included 30 patients with UPJO who underwent laparoscopic pyeloplasty in 2018-2021. Results: Postoperative complications developed rarely, and their frequency and severity were comparable. Independent predictors of UPJO recurrence were the spine osteochondrosis >II period (HR 13.97; 95% CI 1.26; 154.8; p=0.032), the concretions self-discharge (HR 28.49; 95% CI 1.78; 455.62; p=0.018), surgical operation duration > 110 minutes (HR 44.7; 95% CI 3.95; 505.4; p=0.002) and previous nephrostomy (HR 1.07; 95% CI 1.02; 1.13; p=0.002). Conclusions: In the surgical treatment of UPJO, it is advisable to use ERPs, as this allows achieving a better treatment quality with comparable results.

show abstract

“…Применение данных материалов способствует увеличению скорости процессов регенерации и минерализации костной ткани. Среди них препараты на основе гидроксиапатита и коллагена наиболее предсказуемы, эффективны и отличаются широким диапазоном возможного применения для устранения дефектов челюстей различной этиологии [9][10][11][12] .…”

Section: Introductionunclassified

Elimination of critical jawbone defects based on the use of xenogeneic collagen membranes and amorphous hydroxyapatite in an experiment

Дьячкова,

Ершов,

Демьяненко

et al. 2024

Clinical Dentistry (Russia)

View full text Add to dashboard Cite

Устранение дефектов челюстей различной этиологии остается актуальным вопросом на протяжении многих лет. Цель работы — анализ остеогенеза в области критических дефектов челюстей лабораторных животных при применении различных сочетаний ксеногенных стоматологических материалов Matriflex (Биофармахолдинг, Москва) в виде крошки гидроксиапатита и коллагеновых мембран двух видов. Проведено исследование на 6 кроликах породы шиншилла. В ходе эксперимента всем животным в области нижней челюсти интраоперационно создавали критические дефекты с их последующим заполнением костнопластическими материалами в 3 сочетаниях (гидроксиапатит, гидроксиапатит и коллагеновая мембрана №1, гидроксиапатит и коллагеновая мембрана №2), а также по одному дефекту без заполнения материалом в качестве контрольного участка естественной регенерации. В послеоперационном периоде проводили оценку локальных отека и гиперемии по балльной системе. Сроки наблюдения составили 3 месяца с последующим выведением животных из эксперимента и забором биоматериала для микрофокусной компьютерной томографии (КТ) и гистологического исследования. По данным контрольных послеоперационных осмотров животных не было получено статистически значимых различий по выраженности отека и гиперемии тканей в области дефектов с различными методами устранения дефектов. По результатам микрофокусной КТ определялось зарастание дефектов от 80 до 100% в области применения гидроксиапатита и коллагеновых мембран, особенно по сравнению с дефектами без заполнения материалами. Гистологическое исследование подтвердило результаты КТ — регенерация была выражена сильнее в области имплантации материалов. Применение ксеногенных материалов Matriflex в виде мембран и гидроксиапатита позволяет практически полностью устранить критические дефекты челюстей в эксперименте и могут быть рекомендованы для клинической практики. Elimination of jaw defects of various etiologies remains a pressing issue for many years. The aim of the work was to analyze osteogenesis in the area of critical defects in the jaws of laboratory animals using various combinations of xenogeneic dental materials Matriflex (Biopharmaholding, Moscow, Russia) in the form of hydroxyapatite crumbs and two types of collagen membranes. . A study was conducted on 6 Chinchilla rabbits. During the experiment, critical defects were created intraoperatively in all animals in the lower jaw area with their subsequent filling with osteoplastic materials in 3 combinations (hydroxyapatite, hydroxyapatite and collagen membrane no. 1, hydroxyapatite and collagen membrane no. 2), as well as one defect each without filling with material as a control area for natural regeneration. In the postoperative period, local edema and hyperemia were count according to the scoring system. The observation period was 3 months, followed by removal of animals from the experiment and collection of biomaterial for microfocus computed tomography (CT) and histological examination. . According to the control postoperative examinations of animals, no statistically significant differences were obtained in the severity of edema and tissue hyperemia in the area of defects treated with different methods. According to the results of microfocus CT, the healing of defects from 80 to 100% was determined in the area of application of hydroxyapatite and collagen membranes, especially compared to defects without filling with materials. Histological examination confirmed the CT results — regeneration was more pronounced in the area of implantation of materials. . The use of xenogeneic materials Matriflex in the form of membranes and hydroxyapatite makes it possible to almost completely eliminate critical jaw defects in experiments and can be recommended for clinical practice.

show abstract

Nonsurgical Treatment of Peri-Implantitis: Case Series

Cited by 5 publications

References 25 publications

Local/Topical Antibiotics for Peri-Implantitis Treatment: A Systematic Review

Local/Topical Antibiotics for Peri-Implantitis Treatment: A Systematic Review

Outcomes of laparoscopic pyeloplasty and impact of an enhanced recovery protocol

Elimination of critical jawbone defects based on the use of xenogeneic collagen membranes and amorphous hydroxyapatite in an experiment

Contact Info

Product

Resources

About