Nonthrombotic Pulmonary Embolism: A Potential Complication of Polyacrylamide Hydrogel Cosmetic Injection

Abstract

Context. Polyacrylamide hydrogel (PAAG) has gained importance as a synthetic soft tissue filling agent. It has been commonly employed by physicians in Europe for facial contouring and soft tissue augmentation. Previously, PAAG is considered nontoxic and well tolerated with a few mild procedural complications. Case Presentation. A 26-year-old female was hospitalized for dry cough, worsening dyspnea, and chest discomfort after 3 hours of multiple PAAG injections in buttocks. The patient's condition deteriorated and rapidly advanced to acute respiratory failure. Therein, the diagnosis of nonthrombotic pulmonary embolism (NTPE) was established on standard set of investigations. She was intubated; corticosteroid and empiric antibiotic therapy was initiated resulting in improvement of her condition. Subsequently, extubation was done, and she was discharged from the hospital after an uneventful recovery. On 1-month follow-up, the patient had no previous symptoms. Conclusion. This report implicates clinicians to maintain a high index of suspicion for NTPE in patients presenting with respiratory symptoms following PAAG usage.

Lungenszintigraphie (Version 3)

“…Intraluminale Verstopfung durch verschiedene biologische und körperfremde Mate-rialien (3), u. a. auch durch Knochenzement nach Vertebroplastie (29) sowie durch Polyacrylamid Hydrogel nach kosmetischer intramuskulärer Anwendung (52). Beide Materialien sind im CT und Röntgenbild sichtbar.…”

Farklı çapraz bağlayıcılar ile hazırlanmış poliakrilamid hidrojellerinin değerlendirilmesi

“…Poliakrilamid; hidrojel tanımlaması yapıldığı günden beri üzerinde en çok çalışılan hidrojel olup, günümüzde absorban ve toprak düzenleyici olarak, atık suların arıtılmasında, kozmetik, kağıt ve tekstil endüstrisinde, elektroforez uygulamalarında yaygın kullanıma sahiptir [1][2][3][4][5][6][7]. Vinilik özellikteki sade monomeri çok kolay polimerleşir ve bu özelliği en çok tercih edilme nedenlerinden birisidir.…”