Nonuremic Calciphylaxis Associated With Hypercalcemia and Rheumatologic Diseases

Abstract

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Uremic Bilateral Breast Calciphylaxis: A Case Report and Literature Review

“…His results showed that calcium accumulated in the walls of the arterioles and capillaries of the dermis and subcutaneous adipose tissue, resulting in ischemic necrosis. Calciphylaxis is seen most often in patients with end-stage renal failure requiring dialysis; however, it is also encountered in non-uremic patients [ 2 , 3 ].…”

Images in Vascular Medicine: Nonuremic calciphylaxis secondary to occult malignancy

“…There are a few case reports describing the association of nonuremic calciphylaxis with vitamin D toxicity, primary hyperparathyroidism, malignancy, alcoholic liver disease, bariatric surgery, and connective tissue disease. [1][2][3] Female sex and anticoagulation have been reported as two important risk factors. 4 Warfarin, specifically, has been hypothesized to promote nonuremic calciphylaxis by inhibiting vitamin K-dependent carboxylation of matrix Gla protein, thereby decreasing inhibition of local calcification.…”