2007
DOI: 10.1113/expphysiol.2007.037317
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Noradrenergic stimulation within midbrain raphe increases electrolyte excretion in rats

Abstract: The present study was carried out to assess the influence of noradrenergic stimulation of the midbrain dorsal (DRN) and median raphe nuclei (MRN) on urinary volume and electrolyte excretion in hydrated rats. Wistar rats were implanted with a guide cannula into the MRN or DRN and then submitted to two intragastric administrations of water in order to attain an increased diuresis. The following treatments were performed.

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“…Of these inputs, serotonergic raphe and orexinergic hypothalamic nuclei have been shown to be critically involved in sleep and wakefulness (Monti and Monti 2007). The LC, a nucleus known to be important for arousal (Aston-Jones 2004), has extensive projections to hypothalamic and raphe nuclei (Barnes and Pompeiano 1991;Cedraz-Mercez, Mecawi et al 2007). In addition, other brainstem structures known to be involved in sleep and wakefulness (e.g., laterodorsal tegmental nucleus, pedunculopontine tegmental nucleus) send projections to the SCN (Bina, Rusak et al 1993;Krout, Kawano et al 2002).…”
Section: Developmental Emergence Of Circadian Rhythmsmentioning
confidence: 99%
“…Of these inputs, serotonergic raphe and orexinergic hypothalamic nuclei have been shown to be critically involved in sleep and wakefulness (Monti and Monti 2007). The LC, a nucleus known to be important for arousal (Aston-Jones 2004), has extensive projections to hypothalamic and raphe nuclei (Barnes and Pompeiano 1991;Cedraz-Mercez, Mecawi et al 2007). In addition, other brainstem structures known to be involved in sleep and wakefulness (e.g., laterodorsal tegmental nucleus, pedunculopontine tegmental nucleus) send projections to the SCN (Bina, Rusak et al 1993;Krout, Kawano et al 2002).…”
Section: Developmental Emergence Of Circadian Rhythmsmentioning
confidence: 99%