Norland optical adhesive (NOA81) microchannels with adjustable wetting behavior and high chemical resistance against a range of mid-infrared-transparent organic solvents

Wägli, Ph.; Homsy, Alexandra; Rooij, N. F. de

doi:10.1016/j.snb.2011.02.005

Cited by 83 publications

(76 citation statements)

References 20 publications

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“…The resulting surface properties of silanized NOA81 are characterized by a sessile drop experiment ( Table 1). The resulting contact angle values confirm that untreated NOA81 channels are mildly hydrophilic 22,27 . Both surface treatments result in a more hydrophobic surface.…”

Section: Characterization Of the Silanized-noa81 Surfacesupporting

confidence: 60%

Stable Free-Standing Lipid Bilayer Membranes in Norland Optical Adhesive 81 Microchannels

et al. 2016

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ABSTRACT. We report a simple, cost-effective and reproducible method to form free-standing lipid bilayer membranes in microdevices made with Norland Optical Adhesive (NOA81).Surface treatment with either alkylsilane or fluoroalkylsilane enables the self-assembly of stable DPhPC and DOPC/DPPC membranes. Capacitance measurements are used to characterize the lipid bilayer and to follow its formation in real-time. With current recordings, we detect the insertion of single α-Hemolysin pores into the bilayer membrane, demonstrating the possibility of using this device for single-channel electrophysiology sensing applications. Optical transparency of the device and vertical position of the lipid bilayer with respect to the microscope focal plane, allows easy integration with other single-molecule techniques, such as optical tweezers. Therefore, this method to form long-lived lipid bilayers finds a wide range of applications, from sensing measurements to biophysical studies of lipid bilayers and associated proteins.

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Section: Characterization Of the Silanized-noa81 Surfacesupporting

confidence: 60%

Stable Free-Standing Lipid Bilayer Membranes in Norland Optical Adhesive 81 Microchannels

et al. 2016

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“…Before the bonding, each substrate is precisely aligned using bonding aligner and an optical microscope. Each substrate then bonded using a Norland optical adhesive [4]. After the Norland optical adhesive is applied to the edge of the substrate, it is then solidified by …”

Section: Introductionmentioning

confidence: 99%

Silicon Prism-based NIR Spectrometer Utilizing MEMS Technology

Jung¹,

Son²,

Kwon³

et al. 2017

Journal of Sensor Science and Technology

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Recently, infrared (IR) spectrometers have been required in various fields such as environment, safety, mobile, automotive, and military. This IR dispersive sensor detection method of substances is widely used. In this study, we fabricated a silicon (Si) prism-based near infrared (NIR) spectrometer utilizing micro electro mechanical system (MEMS) technology. Si prism-based NIR spectrometer utilizing MEMS technology consists of upper, middle, and lower substrates. The upper substrate passes through the incident IR ray selectively. The middle substrate, acting as a prism, disperses and separates the incident IR beam. The lower substrate has an amorphous Si (a-Si)-based bolometer array to detect the IR spectrum. The fabricated Si prism-based NIR spectrometer utilizing MEMS technology has the advantage of a simple structure, easy fabrication steps, and a wide NIR region operating range.

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“…This modification method is simple and inexpensive, and most importantly, can modify the relatively closed inwall of the capillary tube, which is difficult using other processes. The products of UV solidifying optical adhesive NOA series has been already used in the related field of biological engineering (Arayanarakool et al, 2010;Dupont et al, 2010;Sollier et al, 2011;Wägli et al, 2011;Mokkapati et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Modification research on in wall of capillary copper tube with Norland optical adhesive 68 in a double stereo PCR microfluidic chip

Wang

et al. 2015

Genet. Mol. Res.

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ABSTRACT. In this study, a Norland optical adhesive 68 (NOA68) film, approximately 2.2 μm thick, was manufactured using ultraviolet solidified NOA68 in apparatus manufacturing film on the inwall of a capillary copper pipe, developed in our laboratory. The roughness of the inwall of capillary copper pipe was improved from Ra = 0.766 to 0.204 μm and the contact angle was improved from approximately 96° to 55°, increasing hydrophilicity. Polymerase chain reaction experiments indicated that the ratio of work pressure in the microfluidic chip before modification to that after modification was 2.71/1, indicating that the extension efficiency increased. Our results provide a basis for the construction of a microform chip based on function integration.

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Norland optical adhesive (NOA81) microchannels with adjustable wetting behavior and high chemical resistance against a range of mid-infrared-transparent organic solvents

Cited by 83 publications

References 20 publications

Stable Free-Standing Lipid Bilayer Membranes in Norland Optical Adhesive 81 Microchannels

Stable Free-Standing Lipid Bilayer Membranes in Norland Optical Adhesive 81 Microchannels

Silicon Prism-based NIR Spectrometer Utilizing MEMS Technology

Modification research on in wall of capillary copper tube with Norland optical adhesive 68 in a double stereo PCR microfluidic chip

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