Normale Physiologie der Atmung

Bühlmann, A; Rossier, P. H.

doi:10.1007/978-3-642-87194-8_1

Cited by 2 publications

(2 citation statements)

References 62 publications

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“…In subgroup 2 another mechanism must be responsible for the slight hypoxia at rest and increasing paCT during exercise. Biihlmann and Rossier [7] have described this phenomenon and discussed a better matching of ventilation during exercise in COPD. There was a large alveolar-arterial paCT gradient [(A-a)p02] at rest in both groups (table II).…”

Section: Mechanisms Of Paü2 Response During Exercisementioning

confidence: 99%

Pulmonary Gas Exchange and Central Hemodynamics at Rest and during Exercise in Patients with Chronic Obstructive Pulmonary Disease

Seibold¹,

Roth²,

Lippert³

et al. 1986

Respiration

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Right-heart catheterization and ergometry with arterial and mixed venous blood gas analysis were performed in 27 patients with a wide range of chronic obstructive pulmonary diseases. The purpose of the examination was to evaluate the risk in patients for lung surgery or to detect additional heart diseases. Patients who developed ex-ertional hypoxia (group 1) were compared with others who did not (group 2). In all patients the steady-state maximal workload was determined by ventilatory dysfunction. Both groups had normal values for mixed venous pO₂ and normal increase of the circulatory parameters during exercise. The patients with exertional hypoxia differed from the others in that they showed no decrease of venous admixture and alveolar-arterial oxygen gradient. In addition, these patients had increasing pCO₂ values at rest compared with exercise, indicating alveolar hypoventilation and ventilation-perfusion mismatching. Because of the good correlation of the absolute values of FEV₁ (forced expiratory volume in 1 s) with pulmonary artery pressures, parameters of gas exchange and working capacity, this lung function parameter seems to have a central role in predicting the functional state of patients with chronic obstructive disease. Ergometry and blood gas analysis should be performed in addition because these values cannot be predicted with the calculated postoperative FEV₁

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Section: Mechanisms Of Paü2 Response During Exercisementioning

confidence: 99%

Pulmonary Gas Exchange and Central Hemodynamics at Rest and during Exercise in Patients with Chronic Obstructive Pulmonary Disease

Seibold¹,

Roth²,

Lippert³

et al. 1986

Respiration

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show abstract

“…Prior to this study, we also had to eliminate small systemic errors in the method. This also in volved the problem of correct volume cor rection to BTPS [1,4,12,[16][17][18]. The liter ature offers different data concerning the question how to handle temperature cor rection in these usually half-open systems [2,3,6,14,15].…”

Section: Introductionmentioning

confidence: 99%

BTPS Correction with Dynamic Spirometers

et al. 1986

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In order to determine the requirements for a proper temperature correction of expired volumes, the temperature of the expired air in the bellows of a dynamic spirometer (Vitalograph) was measured in 10 and 5 subjects at 24 and 12.2°C ambient temperature, respectively. During the short period of forced expiration there was a significant temperature decrease, which showed a linear relationship to the ambient temperature. Temperature differences up to 12–15% occurred within seconds; consequently, the values obtained in bellows-type spirometers for FEVi and FVC have to be corrected to BTPS at room temperature. There was no correlation between the degree of temperature decrease and the magnitude of expiratory volume. For routine clinical work it suffices to use the room temperature as the variable.

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Normale Physiologie der Atmung

Cited by 2 publications

References 62 publications

Pulmonary Gas Exchange and Central Hemodynamics at Rest and during Exercise in Patients with Chronic Obstructive Pulmonary Disease

Pulmonary Gas Exchange and Central Hemodynamics at Rest and during Exercise in Patients with Chronic Obstructive Pulmonary Disease

BTPS Correction with Dynamic Spirometers

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