Normalization of intraoperative parathyroid hormone does not predict normal postoperative parathyroid hormone levels

Multidetector CT in diagnostic work-up of patients with primary hyperparathyroidism

“…In addition, intraoperative PTH assays, done after the lesion has been excised, provide a valuable indication of effective remission, as they allow one to exclude other abnormal glands and therefore to perform, in the absence of contralateral thyroid disease, a unilateral neck exploration only [16]. On the other hand, precise preoperative localisation is a prerequisite for planning minimally invasive surgery, a technique proposed by various groups, especially in the absence of goitre [17,18].…”

“…The reasons for this include the cytologist's inability to distinguish assenza di tireopatia controlaterale, solo l'esplorazione monolaterale del collo [16]. D'altronde l'esatta identificazione pre-operatoria della lesione rappresenta un requisito indispensabile per una programmazione dell'intervento chirurgico con approccio mini-invasivo, tecnica quest'ultima proposta da vari gruppi, specie in assenza di concomitante gozzo [17,18].…”

Parathyroidectomy: Overview of the Anatomic Basis and Surgical Strategies for Parathyroid Operations

“…Eighty-eight percent of patients meet these criteria with a 5-min sample and 95% of patients with a 10-min sample [29]. The turn-around time for intraoperative PTH measurement varies from 10 to 18 min [31], but can be longer. An example of IOPTH monitoring in a patient whose hyperparathyroidism was cured following resection of a solitary parathyroid adenoma is illustrated in Fig.…”

Minimally invasive endoscopic-assisted parathyroidectomy for primary hyperparathyroidism

“…The reliability of intraoperative quick PTH assay in confirming surgical success or predicting multiglandular disease has been confirmed in many studies [2, 4, 6, 9, 10, 12-14, 17, 27] although this technique is not without its potential pitfalls [8,10,15,23,24].…”