Normative data for the Montreal Cognitive Assessment (MoCA) in a population-based sample

Nasreddine, Ziad; Rossetti, Heidi; Phillips, Natalie A.; Chertkow, Howard; Lacritz, L; Cullum, C. Munro; Weiner, Myron

doi:10.1212/01.wnl.0000413072.54070.a3

Cited by 108 publications

(70 citation statements)

References 4 publications

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“…10 Had the same strict criteria been applied to the community subjects in Rossetti et al's study, their results may have been similar to the Montreal cutoff scores. 23 Taken together, our two studies suggest that vascular disease is associated with a much higher rate of subtle cognitive impairment than was previously recognized. Given that approximately half of elderly individuals have some brain pathology at death, 24 we would hesitate to apply norms derived from a community sample rather than subjects with stricter criteria of admission to a normative comparison group: doing so would underestimate the rate of MCI associated with vascular or degenerative disease.…”

Section: Discussionsupporting

confidence: 59%

High Incidence of Preoperative Mild Cognitive Impairment in Elderly Surgical Patients

Newman

Cummings²,

Chertkow³

et al. 2014

CJGIM

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Section: Discussionsupporting

confidence: 59%

High Incidence of Preoperative Mild Cognitive Impairment in Elderly Surgical Patients

Newman

Cummings²,

Chertkow³

et al. 2014

CJGIM

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“…However, this cut-off is debated in the literature since age, education level, cultural origin, and the screening conditions of the population studied [29] appear to influence the results of the test [30, 31]. According to the author who promoted the MoCA score, one point should be added to the total score in subjects with a low (<12 years) education level [27], although this was contradicted by Gagnon et al [32].…”

Section: Methodsmentioning

confidence: 99%

Investigation of Cognitive Improvement in Alcohol-Dependent Inpatients Using the Montreal Cognitive Assessment (MoCA) Score

Pelletier¹,

Nalpas

Alarcon³

et al. 2016

Journal of Addiction

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Background. Cognitive dysfunction is a common feature in alcohol use disorders. Its persistence following alcohol detoxification may impair quality of life and increase the risk of relapse. We analyzed cognitive impairment changes using the Montreal Cognitive Assessment (MoCA) score in a large sample of alcohol-dependent inpatients hospitalized for at least 4 weeks. Method. This was an observational longitudinal survey. Inclusion criteria were alcohol dependence (DSM-IV) and alcohol abstinence for at least one week. The MoCA test was administered on admission and at discharge. Results. 236 patients were included. The mean MoCA score significantly increased from 22.1 ± 3.7 on admission to 25.11 ± 3.12 at discharge. The corresponding effect-size of improvement was high, 1.1 [95% CI 1.0–1.2]. The degree of improvement was inversely correlated with the baseline MoCA score. The rate of high and normal, that is, >26, MoCA values increased from 15.8% on admission to 53.8% at discharge. MoCA score improvement was not correlated with the total length of abstinence prior to admission. Conclusion. The MoCA score seems to be a useful tool for measuring changes in cognitive performance in alcohol-dependent patients. A significant improvement in cognitive function was observed whatever the degree of impairment on admission and even after a long abstinence period.

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“…ICIQ-FLUTS [30]/ICIQ-MLUTS [31], IPSS [33], IIEF [35] /FSFI [36], Swiss German OAB [34], ICIQ-LUTSqol [37], Qualiveen [32], HADS [38], MoCA [39]).…”

Section: Methods and Designmentioning

confidence: 99%

Protocol for a prospective, randomized study on neurophysiological assessment of lower urinary tract function in a healthy cohort

et al. 2016

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BackgroundLower urinary tract symptoms are highly prevalent and a large proportion of these symptoms are known to be associated with a dysfunction of the afferent pathways. Diagnostic tools for an objective and reproducible assessment of afferent nerve function of the lower urinary tract are missing. Previous studies showed first feasibility results of sensory evoked potential recordings following electrical stimulation of the lower urinary tract in healthy subjects and patients. Nevertheless, a refinement of the methodology is necessary.MethodsThis study is a prospective, randomized trial conducted at Balgrist University Hospital, Zürich, Switzerland. Ninety healthy subjects (forty females and fifty males) without lower urinary tract symptoms are planned to be included in the study. All subjects will undergo a screening visit (including standardized questionnaires, 3-day bladder diary, urinalysis, medical history taking, vital signs, physical examination, neuro-urological examination) followed by two measurement visits separated by an interval of 3 to 4 weeks. Electrical stimulations (0.5Hz-5Hz, bipolar, square wave, pulse width 1 ms) will be applied using a custom-made transurethral catheter at different locations of the lower urinary tract including bladder dome, trigone, proximal urethra, membranous urethra and distal urethra. Every subject will be randomly stimulated at one specific site of the lower urinary tract. Sensory evoked potentials (SEP) will be recorded using a 64-channel EEG cap. For an SEP segmental work-up we will place additional electrodes on the scalp (Cpz) and above the spine (C2 and L1). Visit two and three will be conducted identically for reliability assessment.DiscussionThe measurement of lower urinary tract SEPs elicited by electrical stimulation at different locations of the lower urinary tract has the potential to serve as a neurophysiological biomarker for lower urinary tract afferent nerve function in patients with lower urinary tract symptoms or disorders. For implementation of such a diagnostic tool into clinical practice, an optimized setup with efficient and reliable measurements and data acquisition is crucial. In addition, normative data from a larger cohort of healthy subjects would provide information on variability, potential confounding factors and cut-off values for investigations in patients with lower urinary tract dysfunction/symptoms.Trial registrationClinicaltrials.gov; Identifier: NCT02272309.

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Normative data for the Montreal Cognitive Assessment (MoCA) in a population-based sample

Cited by 108 publications

References 4 publications

High Incidence of Preoperative Mild Cognitive Impairment in Elderly Surgical Patients

High Incidence of Preoperative Mild Cognitive Impairment in Elderly Surgical Patients

Investigation of Cognitive Improvement in Alcohol-Dependent Inpatients Using the Montreal Cognitive Assessment (MoCA) Score

Protocol for a prospective, randomized study on neurophysiological assessment of lower urinary tract function in a healthy cohort

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