North American blastomycosis with oral lesions

Bell, William A.; Gamble, Jack W.; Garrington, George E.

doi:10.1016/0030-4220(69)90348-x

Cited by 21 publications

(11 citation statements)

References 20 publications

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“…In a study of 40 patients with blastomycosis, one‐quarter demonstrated oral or nasal lesions (81). In another study, 7 of 10 patients had nonspecific oral ulcerations in addition to systemic disease (78).…”

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 95%

“…Oral lesions may arise through disseminated blastomycosis (65,77). Oral blastomycosis is uncommon and may present as single or multiple ulcerations, sessile projections, and granulomatous or verrucous lesions (76,78–80). In a study of 40 patients with blastomycosis, one‐quarter demonstrated oral or nasal lesions (81).…”

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%

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Candidiasis and other fungal diseases of the mouth

2002

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The advent of the human immunodeficiency virus (HIV) and the increasing prevalence of immunocompromised individuals due to surgical and medical advances have resulted in a resurgence of opportunistic infections including oral candidiasis and other rare mycoses which were once considered exotic. It is now recognized that oral candidiasis may present in many clinical guises that may confound the unwary clinician. Other mycotic diseases such aspergillosis, cryptococcosis, histoplasmosis, and mucormycosis may manifest intraorally both as primary lesions and as secondary manifestation of systemic disease. The primary oral pathology of most of the latter mycoses is ulcerations that respond well to systemic therapy with the polyene, amphotericin B. In general, the management of oral fungal infections has been revolutionized by the triazole group of drugs, fluconazole and itraconazole, although recent reports indicate an alarming increase of resistant organisms in particular to fluconazole. The first part of this review attempts to provide an overview of clinical variants of oral candidiasis and current therapeutic techniques, while the latter part outlines the rare oral mycoses and their management.

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Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 95%

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%

Candidiasis and other fungal diseases of the mouth

2002

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“…Various fungal infections can cause oral ulcerations including Aspergillus fumigatus or Aspergillus flavus (aspergillosis), Blastomyces dermatidis (blastomycosis), Histoplasma capsulatum (histoplasmosis), Cryptococcus neoformans (cryptococcosis), Coccidioides immitis (coccidioidomycosis), and Paracoccidiodes brasiliensis (paracoccidiomycosis). Nearly all these infections occur in disseminated forms in immunocompromised individuals [31][32][33][34][35][36]. Ulcerations of aspergillosis appear as black or yellow necrotic lesions which most commonly affect the tongue or palate [31,32].…”

Section: Fungal: Deep Fungal Infectionsmentioning

confidence: 99%

Ulcerated Lesions of the Oral Mucosa: Clinical and Histologic Review

Fitzpatrick

Cohen

Clark

2019

Head and Neck Pathol

141

103

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Ulcerated lesions of the oral cavity have many underlying etiologic factors, most commonly infection, immune related, traumatic, or neoplastic. A detailed patient history is critical in assessing ulcerative oral lesions and should include a complete medical and medication history; whether an inciting or triggering trauma, condition, or medication can be identified; the length of time the lesion has been present; the frequency of episodes in recurrent cases; the presence or absence of pain; and the growth of the lesion over time. For multiple or recurrent lesions the presence or history of ulcers on the skin, genital areas, or eyes should be evaluated along with any accompanying systemic symptoms such as fever, arthritis, or other signs of underlying systemic disease. Biopsy may be indicated in many ulcerative lesions of the oral cavity although some are more suitable for clinical diagnosis. Neoplastic ulcerated lesions are notorious in the oral cavity for their ability to mimic benign ulcerative lesions, highlighting the essential nature of biopsy to establish a diagnosis in cases that are not clinically identifiable or do not respond as expected to treatment. Adjunctive tests may be required for final diagnosis of some ulcerated lesions especially autoimmune lesions. Laboratory tests or evaluation to rule out systemic disease may be also required for recurrent or severe ulcerations especially when accompanied by other symptoms. This discussion will describe the clinical and histopathologic characteristics of a variety of ulcerated lesions found in the oral cavity. KeywordsOral ulcer • Herpetic gingivostomatitis • Aphthous stomatitis • Oral erythema multiforme • Oral medication related ulcer • Oral lichen planus • Oral vesiculobullous lesions • Traumatic oral ulcer • Oral squamous cell carcinoma • Oral lymphoma

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“…Oral lesions may arise through disseminated blastomycosis (81, 113). Oral blastomycosis is uncommon and may present as single or multiple ulcerations, sessile projections, and granulomatous or verrucous lesions (13, 79, 91, 98). In one study of 40 patients with balstomycosis, one‐quarter demonstrated oral or nasal lesions (133) and in another study, seven of ten patients had nonspecific oral ulcerations in addition to systemic disease (13).…”

Section: Oral Manifestations Of Uncommon Systemic Mycosesmentioning

confidence: 99%