Abstract. Based on the CMIP5-generation previous IPSL earth system model, we designed a new version, IPSL-CM5A2, aiming at running multi-millennial simulations typical of deep-time paleoclimates studies. Three priorities were followed during the set-up of the model: (1) improving the overall model computing performance, (2) overcoming a persistent cold bias depicted in the previous model generation, and (3) making the model able to handle the specific continental configurations of the geological past. Technical developments have been performed on separate components and on the coupling system to speed up the whole coupled model. These developments include the integration of hybrid parallelization MPI-OpenMP in LMDz atmospheric component, the use of a new library to perform parallel asynchronous input/output by using computing cores as “IO servers”, the use of a parallel coupling library between the ocean and the atmospheric components. The model can now simulate ~100 years per day, opening new possibilities towards the production of multi-millennial simulations with a full earth system model. The tuning strategy employed to overcome a persistent cold bias is detailed. The confrontation of an historical simulation to climatological observations shows overall improved ocean meridional overturning circulation, marine productivity and latitudinal position of zonal wind patterns. We also present the numerous steps required to run the IPSL-CM5A2 for deep-time paleoclimates through a preliminary case-study for the Cretaceous. Namely, a specific work on the ocean model grid was required to run the model for specific continental configurations in which continents are relocated according to past paleogeographic reconstructions. By briefly discussing the spin-up of such a simulation, we elaborate on the requirements and challenges awaiting paleoclimate modelling in the next years, namely finding the best trade-off between the level of description of the processes and the computing cost on supercomputers.