This paper proffers some guidelines for using a surfactant-polymer (SP) flooding operation so that the feasibility and profit can be optimized. Many successful projects have shown that surfactant-polymer flooding is an effective means to improve oil recovery after or during water-flooding. Here, the guidelines for evaluating whether a surfactant-polymer flood is suitable for a given field are developed and the procedure for a full implementation is summarized. These guidelines cover primary screening, laboratory measurements, reservoir simulation, economic analysis, pilot testing, and field application. Detailed methods also are presented for the optimization of chemicals (including compatibility tests between chemicals and reservoir fluids and rock), well pattern and spacing preparation, and slug and injection process design. The correlations between the above phases of operation are also emphasized. The work offers reservoir engineers a reference for decision-making in SP flooding.