In the Subarctic Pacific, variability in productivity on glacial‐interglacial timescales is often attributed to changes in stratification and nutrient delivery to the surface, but the mechanisms driving this relationship are poorly constrained. Records extending beyond the last glacial maximum from both the open ocean and the marginal seas are required to investigate the timing and magnitude of different influential processes through the full glacial cycle. In this study we generated 231Pa/230Th over 210,000 years in order to capture two full glacial cycles of paleoproductivity on the Juan de Fuca Ridge in the East Subarctic Pacific. The sedimentary 231Pa/230Th ratios are always equal to or greater than the seawater production ratio (0.093), consistent with enhanced biological scavenging in this region. The temporal pattern of 231Pa/230Th burial is remarkably coherent with changes in climate, with high values (0.20) during peak interglacial periods descending to low values (0.10) during peak glacial conditions, consistent with other long productivity records from this region. We investigate the possible contributions of temperature, sea ice formation, Bering Strait closure, wind strength, upwelling, and subsurface nutrient concentrations as possible mechanisms by which physical and/or chemical stratification emerged during glacial periods. Due to the low sea surface salinity in the North Pacific, cooling actually weakens the density gradient in surface (0–200 m) waters. To create the steep density profiles that characterize physical stratification, additional processes to reduce the salinity of surface waters must occur during glacial periods. We suggest that regional sea ice formation and Bering Strait closure may have contributed to freshening surface waters and enhancing physical stratification during glacial periods. Additionally, simulated weak winds in this region due to the southward shift of the glacial westerlies may have further reduced surface mixing depths in the Subarctic Pacific. Finally, previous model simulations suggest strong glacial wind stress curl in the Subarctic Pacific, but enhanced Ekman divergence of nutrient‐poor subsurface waters would have little impact on stimulating productivity in surface waters of the Subarctic Pacific. We therefore suggest that the combined effects of surface freshening, weak winds, and lower subsurface nutrient concentrations may all have contributed to lower productivity during glacial periods in the Subarctic Pacific.