Nortriterpenoids and Lignans from the Fruit of Schisandra chinensis

Xue, Yongbo; Zhang, Yanlong; Yang, Jianhong; Du, Xue; Pu, Jian‐Xin; Zhao, Wei; Li, Xiaonian; Xiao, Wei‐Lie; Sun, Han‐Dong

doi:10.1248/cpb.58.1606

Cited by 41 publications

(23 citation statements)

References 35 publications

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“…The latest studies report on newly identified structures from this group of lignans, which have been given the name schisanchinins A–D (Hu et al 2014), and the first example of naturally occurring N -containing lignan featuring a nicotinoyl group—nicotinoylgomisin (Shi et al 2014b). In addition, other types of lignans have been isolated from the fruits of S. chinensis —dibenzylbutanes lignans: schineolignans A–C, and tetrahydrofuran lignans: schinlignins A and B (Xue et al 2010; Zhang et al 2014b) (Table 3). …”

Section: Characteristic and Current Data On Chemical Compositionmentioning

confidence: 99%

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Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies

Szopa

Ekiert²

2016

Phytochem Rev

269

215

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Schisandra chinensis Turcz. (Baill.) is a plant species whose fruits have been well known in Far Eastern medicine for a long time. However, schisandra seems to be a plant still underestimated in contemporary therapy still in the countries of East Asia. The article presents latest available information on the chemical composition of this plant species. Special attention is given to dibenzo cyclooctadiene lignans. In addition, recent studies of the biological activity of dibenzocyclooctadiene lignans and schisandra fruit extracts are recapitulated. The paper gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential. The cosmetic properties are depicted, too. The analytical methods used for assaying schisandra lignans in the scientific studies and also in industry are also presented. Moreover, special attention is given to the information on the latest biotechnological studies of this plant species. The intention of this review is to contribute to a better understanding of the huge potential of the pharmacological relevance of S. chinensis.

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Section: Characteristic and Current Data On Chemical Compositionmentioning

confidence: 99%

“…In addition, other types of lignans have been isolated from the fruits of S. chinensis —dibenzylbutanes lignans: schineolignans A–C, and tetrahydrofuran lignans: schinlignins A and B (Xue et al 2010; Zhang et al 2014b) (Table 3). …”

Section: Characteristic and Current Data On Chemical Compositionmentioning

confidence: 99%

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies

Szopa

Ekiert²

2016

Phytochem Rev

269

215

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“…1) Previous phytochemical investigation on the fruits of S. chinensis has resulted in the isolation of numerous lignans 2,3) and nortriterpenoids. 4) Although diverse pharmacological effects such as anti-hepatotoxic, anti-inflammatory, anti-oxidant and anti-tumor activities of the fruits of S. chinensis and dibenzocyclooctadiene lignans have been reported, 5,6) there are just few phytochemical or pharmacological investigations on the leaves, stems, or roots of S. chinensis. 7) Therefore, as part of our ongoing project to search novel secondary metabolites from medicinal plants, we chose the roots of S. chinensis for detailed phytochemical study.…”

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confidence: 99%

Schisandrosides A–D, Dibenzocyclooctadiene Lignan Glucosides from the Roots of <i>Schisandra chinensis</i>

Kim

Ryu

Lee

et al. 2015

CHEMICAL & PHARMACEUTICAL BULLETIN

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Four new dibenzocyclooctadiene lignan glucosides, schisandrosides A-D (1-4), as well as two known rare nortriterpenoids, micrandilactone C (5) and propindilactone Q (6), were isolated from the roots of Schisandra chinensis BAILLON (Schisandraceae). The structure of compounds 1-4 were elucidated by physical and spectroscopic data interpretation. To the best of our knowledge, schisandrosides A-D (1-4) represent the first example of a dibenzocyclooctadiene lignan glycoside.

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“…In the last few years, considerable efforts of our research group have been devoted to the phytochemical investigations on fruits, leaves, and stems of S. chinensis (Turcz.) Baill collected from different regions of China; this work resulted in identification of several tetrahydrofuran and dibenzyl butane lignans (Xue et al, 2010), as well as several structurally intriguing Schisandra nortriterpenoids with various beneficial pharmacological effects (Huang et al, 2007a(Huang et al, ,b,c, 2008Shi et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Nortriterpenoids and Lignans from the Fruit of Schisandra chinensis

Cited by 41 publications

References 35 publications

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies

Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies

Schisandrosides A–D, Dibenzocyclooctadiene Lignan Glucosides from the Roots of <i>Schisandra chinensis</i>

Isolation and anti-hepatitis B virus activity of dibenzocyclooctadiene lignans from the fruits of Schisandra chinensi s

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