Nose-to-nose transmission of Salmonella Typhimurium between weaned pigs

Oliveira, Celso José Bruno de; Garcia, T.B.; Carvalho, Luis Felipe das Chagas e Silva de; Givisiez, Patrícia Emília Naves

doi:10.1016/j.vetmic.2007.05.032

Cited by 19 publications

(10 citation statements)

References 12 publications

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“…Therefore, when young animals are confined to high-density situations (as in practical pig rearing conditions), they are in intensive contact with the excreta of other pigs or other environmental factors (pen separations, pig bodies). However, airborne contamination or nose-to-nose transfer cannot be ruled out, as shown in recent studies (23,24). Shedding and spreading of Salmonella in this model could have been encouraged because of the high challenge dose (4), because of the stress of the seeder piglets imposed by the transfer (5), because of the explorative behavior of recently weaned piglets, and likely, even more importantly, because of the temporary incompetence of the immune system and gut barrier function in this period after weaning, promoting coloniza tion of gut lumen and tissues.…”

Section: Discussionmentioning

confidence: 99%

Effect of Organic Acids on Salmonella Colonization and Shedding in Weaned Piglets in a Seeder Model

Michiels

Missotten

Rasschaert³

et al. 2012

Journal of Food Protection

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Piglets (n = 128) weaned at 21 days of age were used in a 35-day seeder model to evaluate the effects of dietary additives differing in active ingredients, chemical, and physical formulation, and dose on Salmonella colonization and shedding and intestinal microbial populations. Treatments were a negative control (basal diet), the positive control (challenged, basal diet), and six treatments similar to the positive control but supplemented with the following active ingredients (dose excluding essential oils or natural extracts): triglycerides with butyric acid (1.30 g kg(-1)); formic and citric acids and essential oils (2.44 g kg(-1)); coated formic, coated sorbic, and benzoic acids (2.70 g kg(-1)); salts of formic, sorbic, acetic, and propionic acids, their free acids, and natural extracts (2.92 g kg(-1)); triglycerides with caproic and caprylic acids and coated oregano oil (1.80 g kg(-1)); and caproic, caprylic, lauric, and lactic acids (1.91 g kg(-1)). On day 6, half the piglets (seeder pigs) in each group were orally challenged with a Salmonella Typhimurium nalidixic acid-resistant strain (4 × 10(9) and 1.2 × 10(9) log CFU per pig in replicate experiments 1 and 2, respectively). Two days later, they were transferred to pens with an equal number of contact pigs. Salmonella shedding was determined 2 days after challenge exposure and then on a weekly basis. On day 34 or 35, piglets were euthanized to sample tonsils, ileocecal lymph nodes, and ileal and cecal digesta contents. The two additives, both containing short-chain fatty acids and one of them also containing benzoic acid and the other one also containing essential oils, and supplemented at more than 2.70 g kg(-1), showed evidence of reducing Salmonella fecal shedding and numbers of coliforms and Salmonella in cecal digesta. However, colonization of tonsils and ileocecal lymph nodes by Salmonella was not affected. Supplementing butyric acid and medium-chain fatty acids at the applied dose failed to inhibit Salmonella contamination in the current experimental setup.

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Section: Discussionmentioning

confidence: 99%

Effect of Organic Acids on Salmonella Colonization and Shedding in Weaned Piglets in a Seeder Model

Michiels

Missotten

Rasschaert³

et al. 2012

Journal of Food Protection

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“…However, the respiratory tract constitutes a portal of entry as well (Fedorka-Cray, Kelley, Stabel, Gray, & Laufer, 1995;Proux et al, 2001). In fact, airborne transmission of Salmonella has been demonstrated in swine (Oliveira, Carvalho, & Garcia, 2006;Oliveira, Garcia, Carvalho, & Givisiez, 2007). Salmonella is able to rapidly spread through the gastrointestinal tract, being shed in the feces within only 2 h postinfection (Boughton, Egan, Kelly, Markey, & Leonard, 2007a, 2007bHurd, Gailey, McKean, & Rostagno, 2001;Rostagno, Eicher, & Lay, in press).…”

Section: Salmonella Infection In Swinementioning

confidence: 99%

Pre-harvest risk factors for Salmonella enterica in pork production

Rostagno

Callaway

2012

Food Research International

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“…A transmissão de Salmonella ocorre, principalmente, pela via fecal-oral e resulta na colonização e invasão do epitélio intestinal, seguida da disseminação para linfonodos e órgãos internos (BOYEN et al, 2008). Porém, a importância da invasão em sítios alternativos, como as tonsilas, seguida de colonização intestinal, já foi demonstrada experimentalmente (FEDORKA-CRAY et al, 1995;OLIVEIRA et al, 2007), indicando que medidas de controle que atuem apenas na colonização intestinal podem não ser eficazes para evitar a infecção dos animais. Em relação ao índice de animais excretando Salmonella nas fezes, ambos os grupos apresentaram uma elevada frequência, não sendo observada diferença significativa entre grupos (Tabela 2).…”

Section: Resultsunclassified

Efeito de probiótico na infecção e excreção fecal de Salmonella em suínos

et al. 2012

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A transmissão de Salmonella na cadeia produtiva de suínos é um problema de difícil controle. O objetivo do estudo foi avaliar o efeito da administração oral de probiótico sobre a ocorrência de infecção e excreção fecal de Salmonella em suínos em fase de crescimento. Os tratamentos consistiram de ração basal sem aditivos (controle) ou adicionada de probiótico (10(7)ufc g-1 de células viáveis dos gêneros Bifidobacterium, Enterococcus, Lactobacillus e Saccharomyces). Foram alocados seis leitões de 50 dias em cada tratamento, com duas repetições por tratamento. Todos os animais foram inoculados com Salmonella Typhimurium (10(6)ufc mL-1) após 14 dias do alojamento. Semanalmente, foram coletadas amostras de sangue e fezes e no dia 35 pós-inoculação os animais foram sacrificados e necropsiados. Os animais de ambos os tratamentos foram infectados por Salmonella e soroconverteram. Não houve diferença (P>0,05) entre os grupos nas médias de Salmonella, Enterococcus, Lactobacillus e coliformes totais nas fezes, porém a administração de probiótico resultou em menor frequência de isolamento de Salmonella a partir de fígado (P=0,04), linfonodos mesentéricos (P=0,04), pulmão (P=0,03) e baço (P=0,01). Conclui-se que os microrganismos probióticos testados não foram capazes de impedir a infecção ou a excreção fecal de Salmonella em suínos de crescimento, mas diminuíram o número de portadores em linfonodos mesentéricos.

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Nose-to-nose transmission of Salmonella Typhimurium between weaned pigs

Cited by 19 publications

References 12 publications

Effect of Organic Acids on Salmonella Colonization and Shedding in Weaned Piglets in a Seeder Model

Effect of Organic Acids on Salmonella Colonization and Shedding in Weaned Piglets in a Seeder Model

Pre-harvest risk factors for Salmonella enterica in pork production

Efeito de probiótico na infecção e excreção fecal de Salmonella em suínos

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