Nosocomial bloodstream infection in a pediatric intensive care unit

Abstract

The predominant organisms responsible for nosocomial infection in the PICU were Klebsiella pneumoniae , Staphylococcus aureus and Enterobacter species . At present, carbapenems plus vancomycin appear to be the best choice for empiric antibiotic therapy in the PICU in Chandigarh.

Nosocomial Bloodstream Infections in Children in Intensive Care Unit: Organisms, Sources, Their Sensitivity Pattern and Outcome of Treatment

“…Some of possible factors for this may be malnourished state of patients, delayed presentation to referral centers and multi-organ involvement at admission. 21 The prevalence of nosocomial infections n ICU in our study is higher than the study of Dusgupta et al 22 19 in neonatal ICU coagulase-negative staphylococci is common isolate in blood culture. Gram-negative bacteria, especially Klebsiella spp., were the predominant causes of neonatal NI, as has been described in other studies from developing countries.…”

Nosocomial Infections and Multidrug-Resistant Bacterial Organisms in the Pediatric Intensive Care Unit

“…Onethird to one-half of all of the S. aureus isolates was noted to be MRSA over the duration of the study. In light of these findings, the authors' choice for empiric antimicrobial coverage was vancomycin and carbapenem [6].…”

“…Although serious infection may prompt admission to the PICU, infection may also be a complication after admission has occurred [2]. Multiple sources have documented that the incidence of nosocomial infections due to antibiotic-resistant organisms is increasing, with specific examples in the Pediatric Intensive Care Unit (PICU) [3][4][5][6].…”

Incidence of Nosocomial Blood Stream Infection, Pneumonia and Urinary Tract Infection Inpediatric Ward at King Abdulaziz University Hospital, Jeddah, Saudi Arabia 2015- 2016.

“…But on the other hand, a study of 841 patients done in tertiary care teaching hospital showed that klebisiella pneumonia was predominant (12).…”

“…Studies had shown that nosocomial infection is strongly associated with prolonged hospital stay and increase the economic burden on the health care system (2). Many studies had shown that the most common organisms are gram-negative bacteria as Klebsiella pneumonia, E-coli, and pseudomonas aeruginosa, followed by gram positive bacteria as staphylococcus aureus, and enterococci (3). The most common type of infections are blood stream infection, followed by pneumonia, and UTI (4).…”