Nosocomial Funguria: Resultant Morbidity and Therapeutic Intervention

Wong-Beringer, Annie; Ra, Jacobs; Bj, Guglielmo

doi:10.1093/clinids/17.6.1066-a

Cited by 8 publications

(1 citation statement)

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“…In contrast to the report of Wong-Beringer et al, 62 candiduria may be an early indicator of systemic infection. 23 A recently published case series suggested a possible benefit of early treatment with fluconazole in critically ill surgical patients at the time of candiduria.…”

Section: Clinical Presentationcontrasting

confidence: 87%

Candida infections in the ICU

Garbino

Pittet

1997

Clinical Intensive Care

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Section: Clinical Presentationcontrasting

confidence: 87%

Candida infections in the ICU

Garbino

Pittet

1997

Clinical Intensive Care

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Community-acquired and hospital-acquired candiduria: comparison of prevalence and clinical characteristics

Colodner

Nuri

Chazan

et al. 2007

Eur J Clin Microbiol Infect Dis

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Hospital-acquired candiduria (HAC) is a well-known finding, related to severely ill patients, prolonged antibiotic treatment, use of catheters, and invasive procedures. However, the risk factors and clinical significance of community-acquired candiduria (CAC) has not yet been described. In this study, the prevalence and clinical characteristics of CAC and HAC were compared. Demographic and clinical data from all patients with positive urinary cultures sent to the bacteriology laboratory of the Haemek Medical Center, Israel, between May 2005 and October 2006 which grew Candida spp. were collected and analyzed. A total of 100,522 urine samples were received, 19,611 (19.5%) of which grew uropathogens. Among them, 204 (125 community-acquired and 79 hospital-acquired) grew Candida spp. (1% of all positive and 0.2% of all samples). Patients with CAC were younger than those with HAC (mean 50.5 years vs. 68.3 years). Pregnant women and bed-ridden patients were more prevalent in CAC (22.5% vs. 1.9% and 46.8% vs. 18.55%, respectively). More patients with HAC suffered from renal failure (27.8% vs. 11.2%) and fever (62.0% vs. 25.6%), had urinary catheters (32.9% vs. 15.2%), and received antibiotic or immunosuppressive therapy in the last month (73.4% vs. 46.4% and 10.1% vs. 3.2%). Most candiduria cases were not treated medically and no further investigation was conducted. Significant differences between patients with CAC and HAC were found. Our results confirm that candiduria (nosocomial as community-acquired) infrequently requires intervention. However, the identification of high-risk patients is desirable and questions regarding the management of candiduria, both CAC and HAC, still remain unresolved.

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High prevalence of upper urinary tract involvement detected by 111indium-oxine leukocyte scintigraphy in patients with candiduria

Horcajada

Gutiérrez‐Cuadra

Martínez-Rodríguez

et al. 2011

Eur J Clin Microbiol Infect Dis

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The purpose of this investigation was to assess the prevalence of upper urinary tract involvement in patients with candiduria by means of (111)indium-oxine-labeled leukocyte scintigraphy. An observational cohort study of patients with confirmed candiduria was conducted in an acute-care teaching hospital in Spain from March 2006 through February 2009. An (111)In-labeled leukocyte scan was performed in order to assess the upper urinary tract involvement. A series of non-matched patients without candiduria nor bacteriuria undergoing scintigraphy to exclude infections in other sites than the urinary tract was also studied. Demographics, baseline illness, and clinical data were recorded. Candiduria was detected in 428 patients, and scintigraphy was performed in 35 of these patients. Twenty-nine patients without candiduria nor bacteriuria were also studied. Positive renal scintigraphy was documented in 24 (68%) patients with confirmed candiduria and in 3 (10%) patients without candiduria (p < 0.005). Renal uptake was not associated with a higher mortality nor with re-admissions. Subclinical pyelonephritis could be more frequent in patients with candiduria than it has been previously considered.

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Nosocomial Funguria: Resultant Morbidity and Therapeutic Intervention

Cited by 8 publications

References 0 publications

Candida infections in the ICU

Candida infections in the ICU

Community-acquired and hospital-acquired candiduria: comparison of prevalence and clinical characteristics

High prevalence of upper urinary tract involvement detected by 111indium-oxine leukocyte scintigraphy in patients with candiduria

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