Nosocomial infection in a neonatal intensive care unit: A prospective study in Taiwan

Su, Bai-Horng; Hsieh, Hsin-Yang; Chiu, Hsiao-Yu; Lin, Hsiao-Chuan; Lin, Hung‐Chih

doi:10.1016/j.ajic.2006.07.004

Cited by 69 publications

(54 citation statements)

References 32 publications

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“…Currently, gram-negative agents are usually found in developing countries and coagulase negative staphyloccocci are reported to be more frequently found in developed countries (22)(23)(24). Efird et al (10) reported that CNS was the most commonly isolated microorganism and K. Pneumonia was the second most commonly isolated microorganism in eight NICU's in USA.…”

Section: Discussionmentioning

confidence: 99%

“…The resistance of gram positive bacteriae against vancomycin and meticillin and the resistance of gram negative bacteriae against third generation cephalosporins have led to significant concern in terms of antibiotic selection. Resistance against third generation cephalosporins develops more rapidly in the presence of combination of penicilin and an aminoglycoside (24,28). Aurangzeb et al (29) reported that gram negative microorganisms in NICU's were resistant to ceftazidime with a rate of 19.4% and resistant to cephotaxim with a rate of 44.8%.…”

Section: Discussionmentioning

confidence: 99%

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Yenidoğan yoğun bakım biriminde hastane kökenli kan akım enfeksiyonları

Bolat¹,

Uslu²,

Bülbül³

et al. 2011

tpa

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H Ho os sp pi it ta al l a ac cq qu ui ir re ed d b bl lo oo od ds st tr re ea am m i in nf fe ec ct ti io on ns s i in n n ne eo on na at ta al l i in nt te en ns si iv ve e c ca ar re e u un ni it t F Fa at ti ih h B Bo ol la at t, , S Si in na an n U Us sl lu u, , A Al li i B Bü ül lb bü ül l, , S Se er rd da ar r C Cö öm me er rt t, , E Em mr ra ah h C Ca an n, , E Ev vr ri im m K K› ›r ra ay y B Ba afl fl, , Ö Öm me er r G Gü ür ra an n, , A As si iy ye e N Nu uh ho o¤ ¤l lu u O Or ri ig gi in na al l A Ar rt ti ic cl le e S Su um mm ma ar ry yAim: The aim of this study was to evaluate the risk factors for term and preterm newborns, etiological agents, antibiotic susceptibility and rate of hospital acquired bloodstream infections among newborns hospitalized in our Neonatal Intensive Care Unit during the year of 2008. Material and Method:The medical records of patients were evaluated retrospectively. The risk factors for term and preterm babies were evaluated by multivariate logistic regression analysis. Results:During the one year period, 807 patients were hospitalized for longer than 72 hours. A total of 97 hemocultures were found to be positive. Among hemoculture positive newborns, 65.6% were found to be preterm and 34.4% term. The most common microorganisms identified were coagulase negative staphylococci and Klebsiella pneumonia. Blood stream infection rate, catheter related blood stream infection rate and ventilator associated pneumonia rate were found to be 5;9:1000 days, 9.6:1000 days and 13.8:1000 days, respectively. Glycopeptide resistance was not observed among gram positive microorganisms. Length of hospital stay, mechanical ventilation and presence of catheter were risk factors for hospital acquired infections. The mortality was found to be 12.5% among newborns with positive hemocultures. Conclusions:Hospital acquired infections are important causes of morbidity and mortality in neonatal intensive care units. The decrement of risk factors in term and preterm newborns would help to improve the outcome. (Turk Arch Ped 2011; 46: 130-6)

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Yenidoğan yoğun bakım biriminde hastane kökenli kan akım enfeksiyonları

Bolat¹,

Uslu²,

Bülbül³

et al. 2011

tpa

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“…16 Turkiye Klinikleri J Med Sci 2011;31 (2) Uy gun suz ve uzun sü re li am pi rik ge niş spek trumlu an ti bi yo tik ku la nı mıy la di renç li bak te ri ler se çil -mek te, bak te ri yel ve in va ziv fun gal en fek si yon ris ki art mak ta dır. 11,12,16,21,22 Ça lış ma mız da da an ti biyo tik kul la nı mı nın risk fak tö rü ola rak tes pit edilme si bu bil gi le ri des tek le mek te dir. Do ğu ma ka dar be be ğin en do jen flo ra sı yok tur.…”

Section: Tar Tiş Maunclassified

“…3,12 Cer ra hi gi ri şim ler, ya ra ye ri en fek si yo nu ve di ğer NE' ler için önem li bir risk fak tö rü ol du ğu gös te ril miş tir. 18,[22][23][24][25] Ça lış -ma mız da cer ra hi gi ri şim sa yı sı az ol mak la bir lik te çok yön lü ana liz ler de risk fak tö rü ola rak tes pit edil miş tir. Cer ra hi gi ri şi min ken di si dı şın da ge tirdi ği an ti bi yo tik pro fi lak si si, has ta ne de ya tı şı uzatma sı, ila ve in va ziv gi ri şim ve te da vi ler gi bi ek fak tör ler de en fek si yon sık lı ğı nı ar tır mış ola bi lir.…”

Section: Tar Tiş Maunclassified

Nosocomial Infections and Risk Factors in Neonatal Intensive Care Unit

Naz¹,

Özgüneş²,

Tekin³

et al. 2011

Turkiye Klinikleri J Med Sci

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Ö ÖZ ZE ET T A Am ma aç ç: : Ça lış ma mız da Ye ni do ğan Yo ğun Ba kım Üni te sinde (YDYBÜ) ya tan tüm has ta lar pros pek tif ola rak in ce le ne rek, no zo ko mi yal en fek si yon (NE) ge li şen ol gu la rın risk fak tör le ri klinik, eti yo lo jik, la bo ra tu var ve te da vi ve ri le ri nin in ce len me si amaç lan mış tır. G Ge e r re eç ç v ve e Y Yö ön n t te em m --l le er r: : Ça lış ma 01 Ocak 2005-01 Ocak 2006 ta rih le ri ara sın da Es ki şe hir Os man ga zi Üni ver si te si Tıp Fa kül te si Pe di at ri Ana bi lim Da lı YDYBÜ' de pros pek tif ola rak ya pıl dı. B Bu ul l g gu u l la ar r: : Ça lış ma pe ri yodun da YDYBÜ'n de ki 545 has ta iz len di. Bu has ta la rın 120'sin de top lam 133 NE ge liş ti. NE hı zı %24.4, in si dans dan si te si 21.3/1000 has ta gü nü ola rak tes pit edil di. Has ta özel lik le ri üze rin de ya pı -lan tek yön lü ana liz ler de dü şük do ğum ağır lı ğı, dü şük ges tas yo nel yaş, res pi ra tu ar dis tres sen dromu ve pe ri na tal as fik si NE' le rin yük sek oran da gö rül me ris ki ile iliş ki li bu lun du. YDYBÜ'n de iz le nen has ta la rın ola sı risk fak tör le ri mul ti var yant lo jis tik reg res yon yön te miy le in ce len di ğin de, NE ge li şen ol gu lar da an ti bi yo tik kul la nı mı (p= 0.002), cer ra hi gi ri şim (p= 0.015), oro gas trik son da uygu la ma sı (p= 0.023) ve has ta ne de ya tış sü re si nin uzun ol ma sı (p= 0.046), NE ge liş me yen ol gu la ra gö -re is ta tis tik sel ola rak an lam lı oran da yük sek ti. NE ta nı sı ile iz le nen has ta la rın çe şit li kül tür le rin de %58.6 (78/133)'sın da et ken izo le edil di. En sık sap ta nan et ken mik ro or ga niz ma lar S.au re us (%21.8), E.co li (%17.9), En te ro bac ter tür le ri (%11.5) ve ko a gu laz ne ga tif sta fi lo kok (%10.2) idi. S So o n nu uç ç: : Yaptı ğı mız çok yön lü ana liz ler de an ti bi yo tik kul la nı mı, cer ra hi gi ri şim, oro gas trik uy gu la ma sı ve hasta ne de uzun ya tış NE ge li şi mi açı sın dan risk fak tö rü ola rak tes pit edil miş tir. Bu bil gi le re da ya na rak NE' le rin ön len me si ne yö ne lik stra te ji le rin ge liş ti ril me si uy gun ola cak tır.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Yo ğun ba kım bi ri mi,ye ni do ğan; risk fak tör le ri A AB BS S T TR RA AC CT T O Ob b j je ec c t ti i v ve e: : In this study, we pros pec ti vely in ves ti ga ted all pa ti ents hos pi ta li zed in the ne o na tal in ten si ve ca re unit (NI CU) and as sessed the eti o lo gi cal fac tors and cli ni cal, la bo ra tory and tre at ment da ta of the pa ti ents who ex pe ri en ced no so co mi al in fec ti ons (NI). M Ma a t te e r ri i a al l a an nd d M Me et t h ho od ds s: : The study was con duc ted pros pec ti vely bet we en Ja nu ary 1, 2005 and Ja nu ary 1, 2006 in NI CU of Es ki se hir Os man ga zi Uni ver sity Fa culty of Me di ci ne, De part ment of Pe di at rics. R Re e--s su ul lt ts s: : Thro ug ho ut the study pe ri od, 545 pa ti ents we re as ses sed. A to tal of 133 epi so des of NI deve lo ped in 120 pa ti ents. Na so co mi al in fec...

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“…The UTIs and surgical site infections comprised only 0.7%. The rate of infection due to medical interventions were about 14% associated with central intravascular catheters, 16% with total parenteral nutrition, 18.6% with ventilator-associated pneumonia, 13.7% with surgeries and 17.3% with urinary catheters (Su et al, 2007).…”

Section: Frequency Of Nosocomial Infectionsmentioning

confidence: 99%

Nosocomial infections in intensive care and medical rehabilitation units, and evaluation of antibiotics prescription

Al-Shenqiti¹,

Bahashwan²,

Ghanem³

et al. 2017

Afr. J. Microbiol. Res.

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Although, nosocomial infections (NIs) are considered to be an important cause of mortality and prolonged stay in hospitals, there are only a few studies that are concerned with their prevention and reduction in rehabilitation units. This could be because most NI surveys have been carried out mainly in acute and long-stay in hospitals. As a result, limited information is available on prevention and reduction of NIs in rehabilitation units. The present study is a systematic review that draws attention to the significance of setting up specific means for infection control in hospital units concerned with critical cases, and stresses on the need to adapt to new infection control policies, training of healthcare professionals, educating patients regarding safety measures and fighting nosocomial infections. Furthermore, this study aims to show the obligations of following certain considerations while prescribing antimicrobial therapy so as to maximize the efficacy and reduce the adverse effects of conventional antibiotics. Systematic review survey methods were adopted throughout the study. Results of the study were debatable concerning the question of predominance of Gram positive or negative microorganisms as nosocomial etiological agents. Infection control measures such as continuous surveillance protocols, suitable prevention methods and appropriate therapeutic treatment strategies such as de-escalation and rotational antibiotic therapies might help reduce nosocomial infections. Much attention should be given in hospitals to the environmental conditions including quality of water and air. Patients with a suppressed immune system during their stay in hospitals are susceptible to levels of microorganisms that are considered safe for a healthy community. Hence, this study suggests that special safety levels should be set up regarding the levels of microorganisms in hospitals and these should be much lower than those used for a healthy community.

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Nosocomial infection in a neonatal intensive care unit: A prospective study in Taiwan

Cited by 69 publications

References 32 publications

Yenidoğan yoğun bakım biriminde hastane kökenli kan akım enfeksiyonları

Yenidoğan yoğun bakım biriminde hastane kökenli kan akım enfeksiyonları

Nosocomial Infections and Risk Factors in Neonatal Intensive Care Unit

Nosocomial infections in intensive care and medical rehabilitation units, and evaluation of antibiotics prescription

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