Nosocomial Infections after Aneurysmal Subarachnoid Hemorrhage: Time Course and Causative Pathogens

Early versus late readmission of subarachnoid haemorrhage patients into neurocritical care

“…Our infection rate is lower than the 37% quoted within the literature. 11 Our results showed an increased trend of WCC and CRP in the patients who were ''failed'' discharges. Although this was not statistically significant, close monitoring of inflammatory makers prior to discharge may prevent early readmission.…”

“…Patients can suffer from electrolyte abnormalities, 2-5 delayed cerebral ischaemia (DCI), 6-8 further bleeding 9,10 and infection. 11,12 These complications are not uncommon, and have been associated with a worse clinical outcome. 13 Once admitted into NCCU, there is no set time period for how long SAH patients should remain for monitoring.…”

Infection prediction for aneurysmal subarachnoid hemorrhage patients at hospital admission: combined panel of serum amyloid A and clinical parameters

“…It has also been suggested that patients' age correlates with the presence of pneumonia [5,17,29]. In the present cohort, all the different types of infection (pneumonia, UTI) were evaluated together, and it was not possible to determine the specific impact of pneumonia infections.…”

“…Pneumonia and urinary tract infections (UTI) are the most prevalent, developing in at least one third of aSAH patients [1,2]. Such infections can significantly impair patients' outcomes, prolonging hospital stays, and increasing associated rates of morbidity and mortality [3][4][5]. Identifying patients at a higher risk of developing an infection is crucial to promptly improve treatment for a potentially long-lasting disability [6,7].…”

Preventive Antibiotics and Delayed Cerebral Ischaemia in Patients with Aneurysmal Subarachnoid Haemorrhage Admitted to the Intensive Care Unit

“…The cause of DCI is multifactorial [2] with one of the postulated underlying mechanisms being the presence of an inflammatory response [3,4]. Infections are seen in up to 30-40 % of patients with aSAH during hospitalisation [5] and signs of systemic inflammation, with or without the presence of an infection, are independent predictors of DCI and poor functional outcome after aSAH [6][7][8][9][10].…”