Nosocomial infections in intensive care units: Etiology and predisposing factors

Kölgelier, Servet; Küçük, Ahmet; Demir, Nazlım Aktuğ; Özçimen, Serap; Demir, Lütfi Saltuk

doi:10.5505/kjms.2012.36036

Cited by 5 publications

(6 citation statements)

References 5 publications

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“…The admission diagnoses of the patients, the presence of immunosuppressive treatment, the exposure and resistance to infectious agents and the resistance to the infectious agents, and the determination of microorganisms and infection in different diagnostic groups also differ (13,14). In a study conducted to determine predisposing factors for infections developing in the intensive care unit in our country, mortality was higher in patients with diabetes mellitus and renal failure, and the mortality rate was lower in patients hospitalized in an intensive care unit after surgical intervention compared with patients admitted to an intensive care unit for other reasons (15).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Nosocomial Infections and Their Relationships with Demographic Data in Four Different Intensive Care Units of an Education and Research Hospital

Gezgel

Yüce

Kuzucuoğlu

et al. 2019

SN Compr. Clin. Med.

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In all units where health care is provided, especially in intensive care units, infection-related complications are conditions that increase the cost and complicate the treatment process. In our study, in 2014-2015, the Ministry of Health Kartal Dr. Data of 1204 patients followed up in intensive care units of Lutfi Kirdar Training and Research Hospital were analyzed. We excluded the patients with antibiotic therapy at admission to the intensive care unit. Cases followed up in the intensive care unit for less than 24 h, and cases with culture detected in the first 48 h were also excluded from the study. Data from 287 patients with culture-positive infections of 743 patients who met the study admission criteria were analyzed. In diagnosing infectious diseases, laboratoryproven blood circulation infections were grouped as catheter-related urinary tract, central venous catheter-related bloodstream infection, ventilator-associated pneumonia, and burn infection. The hospital infections detected in our intensive care units and the determination of the causative pathogens were evaluated according to the differences in these infections according to years, units, diagnoses, demographic data, and clinical presentations. It was determined that hospitalization diagnoses, presence of comorbid diseases, and the percentage of burns were firmly related to the duration of ICU stay and mortality. Acinetobacter baumannii infections were significantly higher in our intensive care units compared with other microorganisms. We aimed to evaluate the data of the patients who were followed up in intensive care units of Dr. Lutfi Kirdar Kartal Training and Research Hospital between 2014 and 2015 with culture-positive infection retrospectively.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Nosocomial Infections and Their Relationships with Demographic Data in Four Different Intensive Care Units of an Education and Research Hospital

Gezgel

Yüce

Kuzucuoğlu

et al. 2019

SN Compr. Clin. Med.

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“…Age, immunity, nutrition of the patient and underlying disease conditions constitute intrinsic risk factors. Extrinsic risk factors are composed of factors related to the health care institution such as the architectural structure of the hospital, failure to observe the asepsis/isolation procedures, and lack of attention to hand washing, disinfection and sterilization (1,(20)(21)(22).…”

Section: Discussionmentioning

confidence: 99%

The Effectiveness of the Antimic® Biocide against Nosocomial Bacteria Specified by Different Standard Methods

Şanli¹,

Menceloǵlu²,

Bal³

2017

Eur J Biol

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The effectiveness of Antimic® (3-(trimethoxysilyl)-propyl, cocodimethylammonium chloride) against different nosocomial pathogens was evaluated. Despite the fact that Antimic® biocide is a recommended compound for disinfecting areas, there is no published data about the antibacterial activity of this formulation against nosocomial pathogens (Acinetobacter baumanii, methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium). The minimum inhibitory/minimum bactericidal effective concentrations for test bacteria were determined. The bactericidal activity of determined dosages was evaluated using the culture-based quantitative suspension test (British Standards BS EN 1276) for 1 and 5-minute contact period, under clean and dirty conditions. Antibacterial activity was also confirmed by fluorescence staining. The biocide was found to be effective at 25 and 50 mg/L concentrations at contact times of 1 and 5 minute, with ≥ 5 log reduction in all bacteria. According to fluorescent microscopic examinations similar bacteria reduction was determined as ≥ 5 log reduction. The results indicated that Antimic® compound meets the requirements of EN 1276 against the tested bacteria. Moreover, Antimic® biocide provide an advantage by not promoting the viable but non culturable state in the tested bacteria and removing the tested bacteria successfully. The results showed that the execution of different microbiological growth and/or antibacterial activity monitoring tests, simultaneously, provide information about the optimum concentration and contact time of a biocide.

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“… 1 - 3 HAI are one of the most frequently-encountered adverse events in providing care and constitute a major public health issue that impacts morbidity, mortality and quality of life. 1 , 2 , 4 , 5 There are many patient and institution-related factors responsible for the high rates of HAI in intensive care units. Patient-related factors include patient’s age, immunity status, chronic illnesses, nutritional status, medications (especially antibiotics) and exposure to catheterization procedures.…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, institution-related factors include high number of patients receiving care in spite of inadequate number of healthcare workers, the architectural structure of the unit, underestimating hand hygiene, disinfection and sterilization practices and not complying with isolation measures. 5 The treatment costs and rates of mortality of infections acquired in intensive care units are substantially high. Thus, monitoring and controlling infections is of great importance.…”

Section: Introductionmentioning

confidence: 99%

Precautions taken by nurses about the prevention of Hospital-Acquired Infections in Intensive Care Units

Kirtil¹,

Akyüz²

2018

Pak J Med Sci

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Objective:To determine the precautions that nurses take for avoiding hospital-acquired infections in intensive care units of a State University Medical Faculty Hospital in Istanbul.Methods:The research data were collected by a questionnaire developed by the authors. The study was conducted in intensive care units of a medical faculty hospital of a state university in Istanbul province. 85 nurses working in different various intensive care units and providing informed consent participated in the study.Results:Intravenous catheterization, urinary catheterization, ventilator-associated infections and surgical site infections were assessed. The questionnaire was scored by applying a conversion of 100 to the total scores obtained, with the highest score being 100 and lowest score being 0. The percentage of nurses that practised all of the approaches about preventing hospital-acquired infections was estimated to be 8.2% for catheter-related bloodstream infections, 67.1% for surgical site infections, 72.9% for catheter-associated urinary tract infections, 27.1% for ventilator-associated infections, 29.4% for isolation preventions and 62.5% for attempts related to sterilization/disinfection of the medical devices.Conclusion:It was seen that nurses use most of the effective measures in order to prevent hospital-acquired infections. The guidelines generated for intensive care units should be updated according to international standards as needed. These guidelines should be used effectively; the differences between intensive care units should be resolved and all nurses should be trained at certain intervals.

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Nosocomial infections in intensive care units: Etiology and predisposing factors

Abstract: AIM:The aim of this study was to evaluate the rate, causes, and predisposing factors of hospital infections in a general intensive care unit. METHODS: The study included 146 patients diagnosed with nosocomial infections following the hospitalization in a general

Cited by 5 publications

References 5 publications

Evaluation of Nosocomial Infections and Their Relationships with Demographic Data in Four Different Intensive Care Units of an Education and Research Hospital

Evaluation of Nosocomial Infections and Their Relationships with Demographic Data in Four Different Intensive Care Units of an Education and Research Hospital

The Effectiveness of the Antimic® Biocide against Nosocomial Bacteria Specified by Different Standard Methods

Precautions taken by nurses about the prevention of Hospital-Acquired Infections in Intensive Care Units

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