Nosocomial infections in the intensive care unit

Trubiano, Jason A; Padiglione, Alexander A

doi:10.1016/j.mpaic.2015.09.010

Cited by 46 publications

(43 citation statements)

References 12 publications

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“…For this reason, numerous studies about the economic and social impact of HAI have been performed over the years [2][3][4]. For example, a European survey from 2011-2012 estimated that the total annual number of patients with HAI in European acute care hospitals was 3.2 million [5].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial and wear performance of Cu-Zr-Al metallic glass composites

et al. 2017

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The antimicrobial and wear behaviour of metallic glass composites corresponding to the Cu 50+x (Zr 44 Al 6 ) 50-x system with x=(0, 3 and 6) has been studied. The three compositions consist of crystalline phases embedded in an amorphous matrix and they exhibit crystallinity increase with increasing Cu content, i.e., decrease of the glass-forming ability. The wear resistance also increases with the addition of Cu as indirectly assessed from H/E r and H

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Section: Introductionmentioning

confidence: 99%

Antimicrobial and wear performance of Cu-Zr-Al metallic glass composites

et al. 2017

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“…A review of emerging MDR bacterial pathogens in ICU includes methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE) and multi-drug resistant Gram-negatives (Nayak et al, 2014;Thompson and FRCP, 2004;Russotto et al, 2015;Trubiano and Padiglione, 2015).…”

Section: Introductionmentioning

confidence: 99%

Multidrug-resistant bacteria isolated from patients hospitalized in Intensive Care Unit in University Hospital of Constantine, Algeria (2011 - 2015)

Hecini-Hannachi¹,

Bentchouala²,

Lezzar³

et al. 2016

Afr. J. Microbiol. Res.

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ICU (26.3, 18.7, 14.3, 11.9 and 9.2% respectively). MRSA strains constituted over 65% of all S. aureus isolates and 30.3% of E. faecium were found to be vancomycin resistant. Extended spectrum β-lactmase producers were expressed in 53.2% and 50.6 from K. pneumoniae and E. coli. Carbapenem resistance among K. pneumoniae improved slightly from 2.89 to 4.21%. A. baumannii isolates exhibited extremely high levels of resistance to all antibiotics except colistin (100% sensitive). In addition, 80.4% of A. baumannii isolates were found to be resistant to imipenem. Imipenem resistant P. aeruginosa isolates showed 36.4%.

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“…In the ICU, the increase in mortality, morbidity and the duration of stay in the hospital is related to nosocomial contamination (described as onset more than forty-eight hours after hospital admission) [13]. So, patients in ICUs are usually at extreme risk of getting infections in order to their diseases, impaired immunity, and exposure to many invasive [14], [15], [16], [17].…”

Section: Hospital-acquired Infections In Nicumentioning

confidence: 99%

“…Usually after 48 -72 hours of patients admitted to ICU, the colonization of nosocomial organisms occurs between them [13]. Whereas that the spread of hospital-acquired infections (HAIs) in Europe ranges from 3.5% to 10%.…”

Section: Bacterial Infections In Nicumentioning

confidence: 99%

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Screening and Prevention of Nosocomial Infections in Neonatal Intensive Care Unit (NICU)

2019

Adv. Environ. Biol

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One of the most causes of patient morbidity and mortality is device-associated healthcare-acquired diseases (DA-HAIs), which is capable of prolonging the length of stay in the intensive care unit (ICU) [7]. Many researches demonstrated that healthcareassociated pathogens repeatedly contaminate the patient's environment. This environment includes both porous surfaces ex: towels and nonporous, hard surfaces ex: table [8]. Whereas, these contaminated surfaces can transmit of pathogens by directly way by Abstract Infants in neonatal intensive care units (NICUs) are usually immunocompromised. So, healthcare-associated infections (HAIs), also known as, nosocomial infections, consider a severe issue for infants in neonatal intensive care units (NICUs). HAIs are described as onset more than 48 hours after hospital admission. In fact, it is responsible for the increase of mortality, morbidity and the duration of stay in the hospital. The rate of HAIs in NICU is range from 6% to 50% per admission. However, this rate rises by 3 to 20-fold in developing countries as contrasted to developed countries. Also, about 2.9 million newborns die yearly during the initial 28 days of their life. Importantly, the environment that surrounds the patients is full by equipment for organ support and monitoring e.g., ventilator, monitors, extracorporeal life support machines. Moreover, the bacteria infectious may come from different resources (e.g., people in the hospital, healthcare' hands, on equipment or surfaces). In fact, HAIs regularly rise as a result of the formation of biofilms at the surfaces of these medical devices. The most gram-positive bacteria that because HAIs are Group B Streptococci, Listeria, Staphylococcus aureus, Methicillin-resistant S. aureus (MRSA). As for gram-negative bacteria such as Escherichia coli, Enterobacter, Klebsiella, Pseudomonas, Serratia, Salmonella…etc., some of these bacteria are resistance for most of the antibiotics. World Health Organization (WHO) put many infection control techniques that may help to reduce the nosocomial infections. Therefore, this review aims to highlight and give brief information about the problem of healthcare-associated infections in NICU and the methods of environmental decontamination in hospitals.

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Nosocomial infections in the intensive care unit

Cited by 46 publications

References 12 publications

Antimicrobial and wear performance of Cu-Zr-Al metallic glass composites

Antimicrobial and wear performance of Cu-Zr-Al metallic glass composites

Multidrug-resistant bacteria isolated from patients hospitalized in Intensive Care Unit in University Hospital of Constantine, Algeria (2011 - 2015)

Screening and Prevention of Nosocomial Infections in Neonatal Intensive Care Unit (NICU)

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