Nosocomial rotavirus infections in neonates: Means of prevention and control

M, Grehn; Kunz, J; Sigg, Peter; Slongo, Rolf; Zbinden, Reinhard

doi:10.1515/jpme.1990.18.5.369

Cited by 15 publications

(8 citation statements)

References 17 publications

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“…During nosocomial and community outbreaks of rotaviral diarrhea, it has been commonly observed that the appearance of respiratory symptom precedes diarrheal phase [1,2,32]. However attempts to recover rotavirus in respiratory mucous specimens have met only a limited success [33][34][35].…”

Section: Discussionmentioning

confidence: 99%

Studies on the survival of aerosolized bovine rotavirus (UK) and a murine rotavirus

Ijaz

Sattar

Alkarmi

et al. 1994

Comparative Immunology, Microbiology and Infectious Diseases

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The effect of relative humidity (RH) and temperature on the survival of airborne bovine rotavirus UK isolate (BRV-UK) and a murine rotavirus (MRV) was studied. In any one experiment, the virus under test was suspended in tryptose phosphate broth (TPB) supplemented with uranine (physical tracer) and an antifoam, was aerosolized using a Collison nebulizer into the rotating drum with the RH at either low (30 +/- 5%), medium (50 + 5%) or high (80 +/- 5%) level at 20 +/- 1 degrees C. Following a 15-min period of viral aerosol stabilization, sequential samples of drum air were collected using an All-Glass Impinger (AGI) for 24 h post-aerosolization. Both of the rotavirus isolates were found to survive best at medium RH level and high RH was found least favorable for the survival of these aerosolized rotaviruses. The survival pattern of aerosolized MRV was found to be the best when compared with survival pattern of all animal and human rotavirus isolates studies performed under aerosolized conditions in our laboratory. The findings of these experiments confirm and extend our previous reports on the survival of other animal and human aerosolized rotaviruses and emphasize the fact that air may be one of the vehicles for their dissemination and could explain why it is difficult to control nosocomial outbreaks of rotavirus gastroenteritis and to keep animal colonies rotavirus-free.

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Section: Discussionmentioning

confidence: 99%

Studies on the survival of aerosolized bovine rotavirus (UK) and a murine rotavirus

Ijaz

Sattar

Alkarmi

et al. 1994

Comparative Immunology, Microbiology and Infectious Diseases

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“…Avoiding placing severely immunosuppressed patients in rooms with other patients is generally preferred. Cohorting has been extensively used for managing outbreaks of MDROs, including MRSA, 22, 806 VRE, 637,807,808 MDR-ESBL, 809 P aeruginosa, 29 MSSA, 810 RSV, 811,812 adenovirus keratoconjunctivitis, 813 rotavirus, 814 and SARS. 815 Modeling studies provide additional support for cohorting patients to control outbreaks; [816][817][818] however, cohorting often is implemented only after routine infection control measures have failed to control an outbreak.…”

Section: Iig Patient Placementmentioning

confidence: 99%

2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Health Care Settings

Siegel¹,

Rhinehart²,

Jackson³

et al. 2007

American Journal of Infection Control

2,728

2,604

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“…Several studies sampled the entire pediatric ward, 6,15,61 whereas other studies only included those children less than 3 years of age 3,4,62 or restricted their analysis to neonates. 13,21,61 Because children less than 3 years of age are much more susceptible to symptomatic RV infection than older children and adults, the incidence rate will be lower if older children are included in the sample, whereas the rate will appear to be higher if younger children alone are selected.…”

Section: Age Of Target Populationmentioning

confidence: 99%