Not All Nonpalpable Breast Cancers Are Alike

Franceschi, Dido; Crowe, Joseph P.; Lie, Sutek; Duchesneau, Renate H.; Zollinger, Robert M.; Shenk, Robert; Stefanek, Gladys; Shuck, Jerry M.

doi:10.1001/archsurg.1991.01410320049005

Cited by 22 publications

(7 citation statements)

References 13 publications

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“…Our study findings refine the known trend that PPV increases with age, showing that calcifications and architectural distortion vary slightly less according to age than do mass and asymmetry at screening and diagnostic examinations (27). The increased prevalence of breast cancer and the decreased prevalence of common benign lesions (eg, cysts, fibroadenomas) according to age Masses at screening examinations are better predictive of cancer among white women than among African American or Hispanic women.…”

Section: Patient Factorssupporting

confidence: 85%

Positive Predictive Value of Specific Mammographic Findings according to Reader and Patient Variables

Venkatesan¹,

Chu²,

Kerlikowske³

et al. 2009

Radiology

135

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Purpose:To evaluate the risk of cancer (positive predictive value [PPV]) associated with specific findings (mass, calcifications, architectural distortion, asymmetry) in mammographic examinations with abnormal results, to determine the distribution of these findings in examinations in which the patients received a diagnosis of cancer and examinations in which the patients did not, and to analyze PPV variation according to radiologist and patient factors. Materials and Methods:HIPAA-compliant institutional review board approval was obtained. PPV of mammographic findings was evaluated in a prospective cohort of 10 262 women who underwent 10 641 screening or diagnostic mammographic examinations with abnormal results between January 1998 and December 2002 in the San Francisco Mammography Registry. The cohort was linked with the Surveillance Epidemiology and End Results program to determine cancer status among these women. PPVs were calculated for each finding and were stratified according to patient characteristics, cancer type, and radiologist reader. Results:Cases of breast cancer (n ϭ 1552) were identified (invasive, n ϭ 1287; ductal carcinoma in situ, n ϭ 270); in five, both kinds of breast cancer were recorded. Overall, of the number of interpretations, masses were most frequently noted in 56%, followed by calcifications in 29%, asymmetry in 12%, and architectural distortion in 4%. Masses, calcifications, architectural distortion, and developing asymmetry demonstrated similar PPVs in screening examinations (9.7%, 12.7%, 10.2%, and 7.4%, respectively), whereas one-view-only and focal asymmetry demonstrated lower PPVs (3.6% and 3.7%, respectively) and were a frequent reason for an abnormal result (42%). Overall, one (5%) in 20 invasive cancers was identified with asymmetry, one (6%) in 16 invasive cancers was identified with architectural distortion, one (21%) in five invasive cancers was identified with calcifications, and two (68%) in three invasive cancers were identified with a mass. Conclusion:Five percent of invasive cancers were identified with asymmetry, and asymmetry is more weakly associated with cancer in screening examinations than are mass, calcifications, and architectural distortion.

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Section: Patient Factorssupporting

confidence: 85%

Positive Predictive Value of Specific Mammographic Findings according to Reader and Patient Variables

Venkatesan¹,

Chu²,

Kerlikowske³

et al. 2009

Radiology

135

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“…Francheschi et al 5 report that in a series of 1144 biopsies performed for positive mammography, none showed see or squamous metaplasia. This may suggest that early detection via mammography is not particularly valuable with see and helps explain the more advanced disease at diagnosis.…”

Section: Resultsmentioning

confidence: 99%

Primary Squamous Cell Carcinoma of the Breast Presenting as a Breast Abscess

Wrightson

Edwards

McMasters

1999

The American Surgeon

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Primary squamous cell carcinoma (SCC) of the breast is a very rare neoplasm, with only 75 cases reported in the English literature. Herein, we report four new cases and discuss the diagnostic and therapeutic challenges of this unusual tumor in a retrospective review of all cases of SCC of the breast at our institution from 1990 to 1998. Four patients with breast SCC were identified, with a mean age of 70 years. Two patients with “pure” SCC (no features of ductal carcinoma) were initially treated for breast abscess. Two other patients with features of both SCC and ductal carcinoma had skin erythema associated with an underlying mass, and infectious etiology was considered in each case. Mean tumor size was 4.9 cm. Both patients with pure SCC underwent extensive evaluation for primary tumors at other sites. Two patients developed early systemic metastasis. SCC of the breast is often diagnosed at an advanced stage and may be confused with breast abscess. For this reason, breast biopsy should be considered in cases of breast abscess. Treatment of primary SCC of the breast is similar to that of more common types of breast cancer (i.e., breast conservation is possible and lymph node dissection is recommended). Because metastasis to the breast from other primary tumor sites has been reported (lung, cervix, skin, and esophagus), patients with pure SCC should undergo evaluation to exclude this possibility.

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“…Un caractère mammographique a été rapporté comme étant évocateur est l'absence de microcalcifications [21]. Pour certains auteurs, le recours à cet examen comme moyen de diagnostic précoce n'est pas valable [22]. Les images radiologiques ne sont pas spécifiques et ils peuvent même prêter confusion avec les images de lésions bénignes.…”

Section: Discussionunclassified

Profils épidémiologiques et diagnostiques des carcinomes épidermoïdes mammaires à l’Institut Joliot Curie de Dakar

Khairane¹,

Charfi²,

Ka³

et al. 2021

Af J Oncol

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INTRODUCTION: Breast cancer is the first cancer in women and clearly constitutes a real public health problem. Although adenocarcinoma remains by far the most common histologic type, there are other types that vary in frequency. A particular form which is the squamous cell carcinoma holds our attention. MATERIALS AND METHODS: The clinical records of patient consultants at the Joliot Curie Institute in Dakar between January 1, 2016 and June 30, 2020 were reviewed. We have retained the cases of pure or mixed breast squamous cell carcinomas. RESULTS: Our study focused on three observations received and treated at the Joliot Curie Institute in Dakar. These patients were 48, 50 and 48 years old respectively. They did not have any particular medical history. They were all postmenopausal. They had consulted following a self-palpation of a breast nodule. The biopsy had concluded in a mammary squamous cell carcinoma. Two of the three patients were metastatic. CONCLUSION: At the end of our study, we recommend a larger scale study including several centers. The therapeutic sequences must be better evaluated and compared to the most frequent form, which is infiltrating ductal adenocarcinoma.

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Not All Nonpalpable Breast Cancers Are Alike

Cited by 22 publications

References 13 publications

Positive Predictive Value of Specific Mammographic Findings according to Reader and Patient Variables

Positive Predictive Value of Specific Mammographic Findings according to Reader and Patient Variables

Primary Squamous Cell Carcinoma of the Breast Presenting as a Breast Abscess

Profils épidémiologiques et diagnostiques des carcinomes épidermoïdes mammaires à l’Institut Joliot Curie de Dakar

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