Not Anytime Soon: The Clinical Translation of Nanorobots and Its Biocompatibility-Interdisciplinarity Critique

Burton, Saheli Datta

doi:10.1007/978-3-030-88615-8_8

Cited by 2 publications

(1 citation statement)

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“…In the literature, less optimistic views on this topic can be found regarding the rapid translation of bioNEMS/MEMS systems into clinical practice. In a recent review, Burton [218] suggests that findings demonstrate that clinical translatability is hampered by insufficient consideration of the biocompatibility of nanorobots with human in-vivo environments in upstream development processes. The design focus is undoubtedly amplified by the absence of meaningful integration with multidisciplinary downstream knowledge.…”

Section: Biocompatibilitymentioning

confidence: 99%

Role of Nanomaterials in the Fabrication of bioNEMS/MEMS for Biomedical Applications and towards Pioneering Food Waste Utilisation

et al. 2022

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bioNEMS/MEMS has emerged as an innovative technology for the miniaturisation of biomedical devices with high precision and rapid processing since its first R&D breakthrough in the 1980s. To date, several organic including food waste derived nanomaterials and inorganic nanomaterials (e.g., carbon nanotubes, graphene, silica, gold, and magnetic nanoparticles) have steered the development of high-throughput and sensitive bioNEMS/MEMS-based biosensors, actuator systems, drug delivery systems and implantable/wearable sensors with desirable biomedical properties. Turning food waste into valuable nanomaterials is potential groundbreaking research in this growing field of bioMEMS/NEMS. This review aspires to communicate recent progress in organic and inorganic nanomaterials based bioNEMS/MEMS for biomedical applications, comprehensively discussing nanomaterials criteria and their prospects as ideal tools for biomedical devices. We discuss clinical applications for diagnostic, monitoring, and therapeutic applications as well as the technological potential for cell manipulation (i.e., sorting, separation, and patterning technology). In addition, current in vitro and in vivo assessments of promising nanomaterials-based biomedical devices will be discussed in this review. Finally, this review also looked at the most recent state-of-the-art knowledge on Internet of Things (IoT) applications such as nanosensors, nanoantennas, nanoprocessors, and nanobattery.

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Section: Biocompatibilitymentioning

confidence: 99%