Ultra-light dark matter (ULDM) refers to a class of theories, including ultra-light axions, in which particles with mass 𝑚 𝜓 < 10 −20 eV comprise a significant fraction of the dark matter. A galactic scale de Broglie wavelength distinguishes these theories from cold dark matter (CDM), suppressing the overall abundance of structure on sub-galactic scales, and producing wave-like interference phenomena in the density profiles of halos. With the aim of constraining the particle mass, we analyze the flux ratios in a sample of eleven quadruple-image strong gravitational lenses. We account for the suppression of the halo mass function and concentration-mass relation predicted by ULDM theories, and the wave-like fluctuations in the host halo density profile, calibrating the model for the wave interference against numerical simulations of galactic-scale halos. We show that the granular structure of halo density profiles, in particular, the amplitude of the fluctuations, significantly impacts image flux ratios, and therefore inferences on the particle mass derived from these data. We infer relative likelihoods of CDM to ULDM