Medicine strives to have evidence-based support for care pathways, and clinicians must rely on a robust, peerreviewed body of literature to make informed decisions. Sorting through all of relevant contemporary literature in any field is a challenging task, which is the reason that Seminars in Cardiothoracic and Vascular Anesthesia has supported the concept of compiling key topics into the annual series called "Noteworthy Literature" for the past 6 years. This year we once again have put together an excellent collection of reviews selected by experts in the disciplines of Cardiothoracic Anesthesiology, Cardiac Critical Care, Cardiothoracic Surgery, Congenital Cardiac Anesthesiology, 844628S CVXXX10.